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Brain zap may stop chemo nerve damage

NCT ID NCT06389721

Prevention Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracks how nerve pain from chemotherapy develops in breast cancer patients. It also tests a brain-stimulating device called a closed-loop brain-computer interface to see if it can prevent that pain. About 45 participants will be observed or receive the experimental stimulation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 45 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2024

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants at MD Anderson Cancer Center

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: Objective 1 Inclusion criteria 1. Participants must have the ability to understand and read English, sign a written informed consent, and be willing to follow protocol requirements. 2. ECOG Performance Status of 0-2; 3. Willing to come to MD Anderson for the imaging sessions. 4. Are 18 years of age or above. 5. Have a diagnosis of breast cancer. 6. will receive chemotherapy including doxorubicin, cyclophosphamide, docetaxel, or paclitaxel; Objective 2 Inclusion criteria: 1\) Inclusion criteria: Identical to Objective 1 and are willing to participate in the therapy sessions at their homes. Exclusion Criteria Objective 1 Exclusion criteria: 1. Participants who are taking any antipsychotic medications. 2. With active CNS disease, such as clinically evident metastases or leptomeningeal disease, dementia, or encephalopathy. 3. Have ever been diagnosed with bipolar disorder or schizophrenia. 4. Known, previously diagnosed peripheral neuropathy from any causes and 5. A history of head injury or who have known seizure activity. Objective 2 Exclusion criteria 1\) Same exclusion criteria as in Objective1. Medication usage will be tracked for patients in all groups. Once prescribed, participants must remain on a stable course of medications throughout the course of chemotherapy.

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Conditions

The condition(s) this trial relates to.

breast cancer chemotherapy-induced neuropathy prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chemotherapy-induced peripheral neuropathy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.