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Laser light offers hope for chemo nerve pain in new trial

NCT ID NCT06834685

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This study tests whether shining a special laser light on painful areas can reduce nerve pain caused by chemotherapy. About 70 cancer survivors with lasting nerve pain will receive either real or placebo laser treatments. The goal is to see if this safe, non-drug approach can improve quality of life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female aged 18 years minimum; * Patient with cancer, whatever the location; * Patient with significant NP defined as a score of 4 at the clinician-rated DN4 ; * Patient with a NP for at least 3 months after the end of an adjuvant or neo-adjuvant chemotherapy; * Women of childbearing potential must have a pregnancy urinary test within a maximum of 7 days before starting the study treatment. A negative result must be documented before study treatment is started. Women without reproductive potential are postmenopausal women or women who have undergone permanent sterilisation (e.g. tubal occlusion, hysterectomy, bilateral salpingectomy); * Effective contraception for women of childbearing age * Patient having signed informed consent prior to any study procedure; * Patient affiliated to a French social protection system; * Patient sufficiently fluent in French to complete questionnaires, as the investigator clinical discretion. Exclusion Criteria: * Patient unable to come twice a week to the investigator center; * Patient unable to sit for a 30-minutes period; * Patient with an open wound or ulcer on the treatment area; * Patient whose diagnosis of peripheral neuropathy is due to another cause (n.b., diabetes without neuropathy will not be a specific exclusion); * Patient with uncontrolled psychiatric illness or neurocognitive impairment that may interfere with assessments, as the investigator clinical discretion; * Patient whose estimated life expectancy is less than 3 months, as estimated by a clinical investigator; * Patient using another concurrent non-pharmacological intervention or complementary therapy for neuropathy during the study; * Patient who has been treated with CAPSAISINE during the previous 3 months; * Patient with pacemaker; * Epileptic patient; * Patient with photosensitive medications, or any medical condition causing sensitivity to light (n.b., Lupus); * Pregnant and/or breastfeeding woman; * Patient with primary tumor and/or metastases in areas to be treated by BPM (i.e., hands and/or feet); * Patient with pre-existing eye disease (such as maculopathy, glaucoma, cataract and retinal lesions), or a history of family eye diseases; * Patient who has been already been treated with photobiomodulation on the area of interest. * Participation in another concomitant clinical study with neuropathic pain or chemo-induced peripheral neuropathy as the primary endpoint. * Presence of a tattoo on the area to be treated.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre Azuréen de Cancérologie

    NOT_YET_RECRUITING

    Mougins, Alpes Maritimes, 06250, France

  • ICM

    RECRUITING

    Montpellier, 34298, France

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