CARDIAC ARREST (CA)

This study tests whether a drug called GC7 can reduce harmful oxidative stress in 20 adults who have been resuscitated after a cardiac arrest. The drug aims to protect cells from damage caused when blood flow returns to the heart and brain. Researchers will measure blood markers …

This study tests whether giving a drug that blocks a key inflammatory protein (TNF-alpha) within 6 hours after a cardiac arrest can improve survival and brain recovery. The trial involves 208 adults who remain unconscious after their heartbeat is restored. The goal is to see if c…

This study tests a new CPR method called Bio-CPR, which combines chest compressions with breathing support in a more natural way. It involves 408 adults who have a witnessed cardiac arrest outside the hospital. The goal is to see if Bio-CPR works better than standard CPR to impro…

This study looks at how often colon damage happens in adults who survive a cardiac arrest and receive CPR. About 200 participants will have a colonoscopy 24-36 hours after CPR to check for colon ischemia. The goal is to understand this complication better, not to test a new treat…

This study reviews medical records of 100 adults who needed a breathing machine after a heart attack or cardiac arrest. Researchers want to see how often acid-base problems occur and compare doctors' ventilator settings with a computer algorithm's suggestions. No new treatments a…

This study aims to see if a portable, low-field MRI can detect brain damage in coma patients after cardiac arrest as well as standard high-field MRI does. Researchers will scan 60 participants (coma patients and healthy volunteers) multiple times over two weeks. The goal is to de…

This study tests a belly tourniquet in 5 adults whose heart stops outside a hospital. The idea is to squeeze the main artery in the belly, sending more blood to the brain and heart. Researchers want to see if this helps restart the heart and reduce brain damage.

This study looks at a new device that can measure a substance called nucleosomes in the blood right at the patient's bedside. Researchers want to see if these levels can help predict which critically ill patients will survive for 30 days. The study will include 130 adults in the …

This study examines whether volunteers who are alerted by a smartphone app can improve survival for people who have a cardiac arrest outside the hospital. Researchers will compare outcomes for about 5,200 adults in Emilia-Romagna, Italy, who either did or did not receive help fro…

This study will collect information from 1,200 patients in the French West Indies and Guiana who have received ECMO, a machine that helps the heart and lungs work. The goal is to understand how these patients fare, including survival rates and complications. No new treatments or …

This study looks at whether people who survive a cardiac arrest outside the hospital recover better if they are treated at a specialized cardiac arrest center instead of a regular hospital. About 1,600 adults will be randomly assigned to either be transferred to a specialty cente…

This study tests whether using a device to precisely control how much air a person gets during CPR can improve their chances of survival. About 852 adults who have a cardiac arrest in the hospital will be randomly assigned to either standard manual breathing help or breathing tai…