Can smart breathing devices save more cardiac arrest patients?
NCT ID NCT07088120
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using special devices to precisely control breathing during CPR can help more people survive a cardiac arrest. About 852 adults who have a cardiac arrest in the hospital will be randomly assigned to either standard manual breathing help or breathing tailored to their body size using real-time monitors. The main goal is to see if more patients regain a pulse and blood flow.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 852 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients (18 years or older) with in-hospital cardiac arrest receiving manual ventilation via bag-mask or artificial airway Exclusion Criteria: * Inability to estimate predicted body weight (e.g., extreme body habitus or lack of height data). * Patients receiving Extracorporeal Membrane Oxygenation (ECMO). * Known pregnancy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites in 2 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Civil Fray Antonio Alcalde, University of Guadalajara
Guadalajara, Jalisco, 44280, Mexico
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Rush University Medical Center
Chicago, Illinois, 60612, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Hand position in CPR: does comfort compromise compression quality?
- Short CPR practice sessions at work may sharpen hospital resuscitation skills
- Front-Back vs. Front-Side: which defibrillator pad placement saves more lives?
- Spinal fluid and blood may reveal how the brain suffers after cardiac arrest
- Blood tests in the ambulance: a new study probes early brain injury markers