ANALGESIA

This study is testing if a single numbing injection, given during ACL knee surgery, helps teens and young adults feel less pain and need fewer opioid pain pills in the week after their operation. Researchers will compare pain and medication use between patients who get the inject…

This study aims to see if adding a drug called neostigmine to a standard pain-blocking injection can better manage pain after a cesarean delivery. Researchers will compare how long pain relief lasts and how much extra pain medication is needed in the first 24 hours after surgery.…

This study aims to see if a specific nerve block combined with a numbing spray can better manage pain after surgery for obstructive sleep apnea. It will involve 80 adults undergoing a procedure called uvulopalatoplasty. The goal is to help patients recover faster, with less pain …

This study is testing two different non-opioid methods to help manage pain after brain tumor surgery. It will involve 2,000 patients to see if using a local nerve block before surgery or a specific sedative during surgery can reduce the need for strong opioid painkillers afterwar…

This study is testing whether a combination of two sedative drugs, esketamine and dexmedetomidine, can better manage severe agitation and confusion (delirium) in intensive care unit (ICU) patients who are awake and on breathing support but not on a ventilator. The main goal is to…

This study aims to find the best nasal spray medication for quickly relieving severe pain in children who come to the emergency room with injuries like broken bones. Researchers will compare two pain-relieving sprays—sufentanil and ketamine—given alongside standard care to see wh…

This study is testing a combination approach to manage pain after brain tumor surgery. It will compare different methods of delivering pain medication to see which best reduces the need for strong opioid drugs. The goal is to find a safer, more effective way to control pain and s…

This study is testing if giving a numbing injection (scalp nerve block) *before* making the skin cut in brain surgery works better for pain than giving it *after* the cut. It aims to reduce the need for strong opioid painkillers and help patients recover more comfortably. The tri…

This study aims to improve pain control and reduce side effects for older adults after heart surgery. Researchers will use genetic testing to try to predict which patients might have severe pain or bad reactions to common opioid pain medications like methadone. The goal is to hel…