ANALGESIA
Clinical trials for ANALGESIA explained in plain language.
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Needle-Free pain relief: nasal sprays tested for kids in emergency
Symptom relief Not yet recruitingThis study tests two nasal sprays, sufentanil and ketamine, to see which works better for severe pain from injuries like broken bones in children aged 6 to 17. Both sprays are given in the emergency room along with standard care. The goal is to find a fast, needle-free way to eas…
Matched conditions: ANALGESIA
Phase: PHASE2 • Sponsor: Fondation Lenval • Aim: Symptom relief
Last updated May 26, 2026 09:42 UTC
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New drug cocktail aims to quiet ICU delirium faster
Symptom relief Not yet recruitingThis study tests whether combining two sedative drugs (esketamine and dexmedetomidine) can safely reduce the time ICU patients spend in a confused, agitated state called hyperactive delirium. About 132 adults on non-invasive breathing support will receive either the drug combo or…
Matched conditions: ANALGESIA
Phase: PHASE4 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Symptom relief
Last updated May 26, 2026 09:40 UTC
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Could a simple additive make C-Section recovery less painful?
Symptom relief Not yet recruitingThis study tests whether adding neostigmine to a standard numbing medicine (bupivacaine) in an ultrasound-guided belly block can provide better pain relief after cesarean delivery. About 58 women having a planned C-section will take part. The goal is to see if this combination de…
Matched conditions: ANALGESIA
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated May 26, 2026 09:29 UTC
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Nerve block may cut Kids' opioid use after ACL surgery
Symptom relief Not yet recruitingThis study looks at whether a single-shot nerve block (using the drug ropivacaine) can reduce pain and the need for strong painkillers in children and teens after ACL knee surgery. About 160 participants aged 13 and older will be randomly assigned to get the nerve block during su…
Matched conditions: ANALGESIA
Phase: PHASE2 • Sponsor: Texas Scottish Rite Hospital for Children • Aim: Symptom relief
Last updated May 26, 2026 09:26 UTC
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New combo may cut opioids and confusion after brain surgery
Symptom relief Not yet recruitingThis study tests if using scalp nerve blocks and a sedative drug called dexmedetomidine can reduce the need for strong opioid painkillers and prevent confusion after brain tumor surgery. About 2000 adults having elective brain surgery will be randomly assigned to one of four trea…
Matched conditions: ANALGESIA
Phase: NA • Sponsor: Beijing Tiantan Hospital • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC
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Scalp block before brain surgery may cut opioid use
Symptom relief Not yet recruitingThis study looks at whether giving a scalp nerve block before the first cut (instead of after) can lower pain and the need for strong painkillers during and after brain surgery. About 64 adults aged 18-65 will take part. The goal is to see if this simple step makes recovery smoot…
Matched conditions: ANALGESIA
Sponsor: Umraniye Education and Research Hospital • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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Heart surgery pain relief gets personal: methadone study aims to cut opioid risks
Symptom relief Not yet recruitingThis study will test whether giving methadone based on a patient's genes can reduce opioid side effects like nausea, vomiting, and breathing problems while improving pain control. Researchers will enroll 400 adults over 60 having heart surgery. The goal is to find the safest, mos…
Matched conditions: ANALGESIA
Sponsor: Kathirvel Subramaniam • Aim: Symptom relief
Last updated May 19, 2026 11:47 UTC
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New pain combo could cut opioid use after brain surgery
Symptom relief Not yet recruitingThis study tests a combination of pain medicines and local numbing to improve pain control after brain tumor surgery. The goal is to reduce the need for strong opioids, which can cause side effects and complications. About 2,000 adults having planned brain surgery will take part.…
Matched conditions: ANALGESIA
Phase: NA • Sponsor: Beijing Tiantan Hospital • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC