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Heart surgery pain relief gets personal: methadone study aims to cut opioid risks

NCT ID NCT05612399

First seen Sep 30, 2025 · Last updated May 19, 2026 · Updated 26 times

Summary

This study will test whether giving methadone based on a patient's genes can reduce opioid side effects like nausea, vomiting, and breathing problems while improving pain control. Researchers will enroll 400 adults over 60 having heart surgery. The goal is to find the safest, most effective way to manage pain after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Presbyterian Hospital

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

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