AMYOTROPHIC LATERAL SCLEROSIS

This study tested a new drug called VRG50635 in 54 adults with ALS to see if it is safe and tolerable. Participants received multiple doses of the drug, and researchers monitored side effects and disease progression. The trial was terminated early, so results are limited.

This early-phase study tested the safety of an experimental drug called DNL747 in 15 people with ALS. The trial was stopped early, so we don't know if the drug helps control the disease or ease symptoms. The main goal was to check for side effects, not to measure any treatment be…

This study tested an experimental drug called BIIB105 in adults with ALS, a disease that weakens muscles over time. The trial had two parts: first, some people got the drug and some got a placebo; then everyone could get the drug for up to 3 years. The study was stopped early, an…

This study tested a new drug, STR04, in people with ALS, a disease that weakens muscles over time. Only one person took part before the study was stopped early. The goal was to see if the drug was safe and if it could slow down the disease, but no clear results are available due …

This study aimed to test several potential drugs for amyotrophic lateral sclerosis (ALS) in one flexible trial. It enrolled 88 adults with ALS to see if any drug could improve survival or slow disease progression. The trial was stopped early, so results are limited.

This study looked at whether the drug BLZ945 is safe and how it affects brain inflammation in people with ALS. Researchers used special PET scans to measure immune cell activity in the brain. The study was stopped early, and it involved 28 adults with ALS.