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ALS drug study halted: brain scans aimed to track inflammation

NCT ID NCT04066244

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 29 times

Summary

This study looked at whether the drug BLZ945 is safe and how it affects brain inflammation in people with ALS. Researchers used special PET scans to measure immune cell activity in the brain. The study was stopped early, and it involved 28 adults with ALS.

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Contacts and locations

Locations

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Novartis Investigative Site

    Turku, 20520, Finland

  • Novartis Investigative Site

    Stockholm, 14186, Sweden

  • Yale University School of Medicine

    New Haven, Connecticut, 06520-8048, United States

Conditions

Explore the condition pages connected to this study.