ADDICTION

This early-phase study tested whether adding a medication called AUVELITY (a mix of dextromethorphan and bupropion) to standard buprenorphine/naloxone treatment is safe for people with opioid use disorder. 18 adults on stable buprenorphine treatment took part. Researchers monitor…

This pilot study tested whether adding protein supplements to the diet could lower cravings in people hospitalized for addiction. 28 participants spent one week with protein supplements and one week without, rating their cravings daily. The goal was to see if protein could ease t…

This study tested whether N-acetylcysteine (NAC), a supplement, can help people who struggle with both alcohol use disorder and PTSD. 182 adults took either NAC or a placebo for a period, and researchers measured changes in drinking habits, cravings, and PTSD symptoms. The goal w…

This study tested whether low-frequency magnetic brain stimulation (rTMS) could reduce tobacco cravings in heavy smokers who had already failed multiple quit attempts. 39 adults who were highly dependent on nicotine and wanted to quit received either real or fake rTMS over two we…

This study looked at whether a program called SKY Recovery, which teaches breathing and meditation, can help people recovering from substance use disorder. About 100 people in a residential treatment center took part. The program included a 5-day workshop and weekly follow-ups. R…

This study tested whether giving a single dose of pregabalin (a nerve pain medication) about an hour before kidney stone surgery could reduce pain and the need for opioid painkillers afterward. 118 adults having ureteroscopy with a ureteral stent were randomly assigned to receive…

This study tested a breathing technique called Holotropic Breathwork to help people recover from addiction. 25 adults in residential treatment or living in the community took part. The goal was to see if the practice is safe, acceptable, and might reduce substance use and improve…

This early-stage study tested whether cannabidiol (CBD) is safe and helpful for people who are being treated for opioid addiction and also have long-term pain. Seven adults on methadone or buprenorphine received CBD or a placebo in a controlled setting. Researchers measured sedat…

This study screened nearly 7,000 volunteers to find people eligible for future research on drug addiction and its effects on the brain and body. Participants completed phone and in-person interviews, medical exams, and lab tests. No treatment or clinical care was provided.

This study used artificial intelligence to analyze personality and behavior data from 155 adults in residential treatment for substance use disorders. The goal was to find hidden patterns that could help doctors tailor treatments to individual patients. No treatment was given; th…

This study tested a training program called First Face, designed to help community members recognize and respond to mental health crises. 92 staff from the Healing Lodge of the Seven Nations took surveys before, right after, and 3 months after training. The goal was to see if the…

This study looked at how to best prevent tuberculosis (TB) in Malaysian prisons, focusing on inmates with and without opioid dependence. Researchers compared two TB prevention treatments: a standard daily medicine for 40 weeks versus a shorter weekly combination for 12 weeks. The…