ACUTE STROKE

This study tests an experimental drug called DM199 in people who have had a moderate stroke and cannot receive standard clot-removal treatments. The goal is to see if DM199 helps improve recovery and reduce disability. About 728 participants will receive either the drug or a plac…

This study looks at 90 stroke patients who need emergency clot removal. It compares two forms of general anesthesia to see which one better maintains blood flow to the brain and improves recovery. The goal is to find the best anesthesia method for future larger trials.

This study looks at whether giving extra nutrition through a vein, in addition to standard tube feeding, can lower the chance of pneumonia in people with severe stroke. About 546 adults who have trouble swallowing will be randomly assigned to one of two feeding plans. The goal is…

This study tests whether giving stroke patients a personalized nutrition plan within 2 days of their stroke can lower the risk of death within 30 days. About 3,084 adults with moderate to severe stroke will take part. A dietitian will check each patient's swallowing and eating ab…

This study tests whether a special blood pressure device (Doctormate) can be used during helicopter transport to help stroke patients with blocked arteries. The device temporarily squeezes the arm to improve blood flow to the brain. The goal is to see if this is practical and saf…

This study tests whether an investigational drug called Dimephosphon can improve recovery in people who have had an acute ischemic stroke (a stroke caused by a blood clot). The trial involves 184 adults aged 35-80 who receive either Dimephosphon or a placebo within 24-72 hours of…

This study tests a new way to treat ischemic stroke using a special suction device called the Zoom System. The goal is to quickly restore blood flow to the brain by removing the clot. About 750 adults who have had a stroke will be enrolled to see if this technique is safe and eff…

This study tests whether a wearable robot can help people who recently had a stroke recover movement in their legs and ankles. The goal is to improve walking, balance, and daily function. The study will include 140 adults aged 18 to 80 who had a first-time stroke within the past …

This study tests whether focusing on one muscle at a time or using natural movement patterns works better for improving arm function after a recent stroke. Forty adults who had a stroke in the last few days will receive either isolated or synergetic muscle therapy plus standard r…

This study tests whether adding mirror therapy to standard physical therapy helps people who recently had a stroke regain arm and hand function. About 44 adults aged 40–55 with a stroke within the past month will take part. Participants will either get usual rehab or usual rehab …

This study looks at whether a simple ultrasound of the voice box can help predict choking or pneumonia risk in people who recently had a stroke. Researchers will check vocal cord movement with ultrasound and then follow 200 patients for one year to see who develops choking or lun…

This study examines blood samples from 500 people who recently had a stroke and healthy volunteers to find RNA patterns that could help diagnose strokes and predict recovery. Researchers will use advanced genetic sequencing to identify potential biomarkers. The goal is to improve…

This study aims to build an AI system that predicts which type of rehabilitation will work best for each stroke survivor. Researchers will collect data from 400 participants, including brain scans, muscle activity, and genetic information, before they receive standard rehab or tr…

This study is building a large registry of people who have had a stroke and still have symptoms. The goal is to connect them with researchers working on new ways to improve recovery. No treatment is given; participation simply involves joining the registry.

This study looks at how well a new clot-busting drug, non-immune staphylokinase, works for people having a stroke. Researchers will compare it to the standard drug alteplase by tracking bleeding risks and other outcomes in about 336 patients aged 18 to 85. The goal is to see if t…

This study looks at whether a tool called the Modified SOAR score can help doctors predict which stroke patients are at highest risk of dying soon after they are admitted to the hospital. Researchers will follow 60 adults with acute stroke for the first 7 days of their stay. The …

This study explores whether simple body measurements, like muscle size and electrical properties, can help predict how well someone will recover after a stroke. Researchers will measure the thickness and surface area of a jaw muscle and use a special scale to assess body composit…