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Viral infectious disease
MONDO:0005108Any disease caused by a virus.
Also known as: Viruses caused disease or disorder, Viruses disease or disorder, Viruses infection, Viruses infectious disease, infection, viral, viral disease, viral disorder, viral infection
4447 clinical trials for this condition and its sub-types, 134 tagged with Viral infectious disease itself.
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Sub-types of Viral infectious disease
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Primary viral infectious disease 0 trials · 4,252 incl. sub-types
32 sub-types
- Viral sexually transmitted disease 5 trials · 1,593 incl. sub-types Sub-types →
- Lentivirus infection 2 trials · 1,569 incl. sub-types Sub-types →
- Nidovirales infectious disease 8 trials · 998 incl. sub-types Sub-types →
- Viral hepatitis 12 trials · 443 incl. sub-types Sub-types →
- Influenza 334 trials · 345 incl. sub-types Sub-types →
- Herpesviridae infectious disease 7 trials · 304 incl. sub-types Sub-types →
- Human papilloma virus infection 297 trials · 303 incl. sub-types Sub-types →
- Hepadnaviridae infectious disease 0 trials · 274 incl. sub-types Sub-types →
- Mononegavirales infectious disease 0 trials · 217 incl. sub-types Sub-types →
- Flaviviridae infectious disease 1 trial · 98 incl. sub-types Sub-types →
- Picornaviridae infectious disease 0 trials · 55 incl. sub-types Sub-types →
- Adenoviridae infectious disease 43 trials · 44 incl. sub-types Sub-types →
- Monkeypox 40 trials
- Bunyaviridae infectious disease 1 trial · 39 incl. sub-types Sub-types →
- Togaviridae infectious disease 0 trials · 32 incl. sub-types Sub-types →
- Deltaretrovirus infections 1 trial · 32 incl. sub-types Sub-types →
- Viral pneumonia 27 trials Sub-types →
- Viral encephalitis 3 trials · 17 incl. sub-types Sub-types →
- Smallpox 15 trials Sub-types →
- Rotavirus infection 12 trials
- Caliciviridae infectious disease 6 trials · 10 incl. sub-types Sub-types →
- Plantar wart 10 trials
- Rubella 9 trials Sub-types →
- Arenaviridae infectious disease 1 trial · 8 incl. sub-types Sub-types →
- Polyomavirus infectious disease 6 trials
- Viral exanthem 0 trials · 3 incl. sub-types Sub-types →
- Viral myocarditis 2 trials
- Cowpox 1 trial
- Astroviridae infectious disease 0 trials
- Aleutian mink disease, human 0 trials
- Phlebotomus fever 0 trials
- Viral pericarditis 0 trials
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Viral respiratory tract infection 47 trials · 566 incl. sub-types
6 sub-types
- Influenza 334 trials · 345 incl. sub-types Sub-types →
- Respiratory syncytial virus infectious disease 168 trials · 170 incl. sub-types Sub-types →
- Common cold 36 trials
- Viral pneumonia 27 trials Sub-types →
- Hantavirus pulmonary syndrome 2 trials
- Viral laryngitis 0 trials
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Coronavinae infectious disease 136 trials
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Disease arising from reactivation of latent virus 4 trials · 89 incl. sub-types
3 sub-types
- Herpes zoster 73 trials Sub-types →
- Genital herpes 8 trials Sub-types →
- Herpes labialis 5 trials Sub-types →
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Viral infection of central nervous system 3 trials · 58 incl. sub-types
7 sub-types
- Poliomyelitis 28 trials · 39 incl. sub-types Sub-types →
- Viral encephalitis 3 trials · 17 incl. sub-types Sub-types →
- Venezuelan equine encephalitis 1 trial
- Lymphocytic choriomeningitis 1 trial
- Central nervous system AIDS arteritis 0 trials
- Geniculate herpes zoster 0 trials
- Meningitis caused by poliovirus 0 trials
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Viral hemorrhagic fever 10 trials · 51 incl. sub-types
16 sub-types
- Ebola hemorrhagic fever 21 trials
- Dengue hemorrhagic fever 7 trials Sub-types →
- Arenavirus hemorrhagic fever 0 trials · 6 incl. sub-types Sub-types →
- Crimean-Congo hemorrhagic fever 5 trials
- Marburg hemorrhagic fever 4 trials
- Rift valley fever 3 trials
- Hantavirus pulmonary syndrome 2 trials
- Venezuelan equine encephalitis 1 trial
- Hemorrhagic fever-renal syndrome 1 trial
- Bolivian hemorrhagic fever 0 trials
- Brazilian hemorrhagic fever 0 trials
- Chapare hemorrhagic fever 0 trials
- Kyasanur forest disease 0 trials Sub-types →
- Lujo hemorrhagic fever 0 trials
- Omsk hemorrhagic fever 0 trials
- Venezuelan hemorrhagic fever 0 trials
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Arbovirus fever 0 trials · 46 incl. sub-types
2 sub-types
- Chikungunya 31 trials
- Yellow fever 16 trials
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Kaposi's sarcoma 45 trials
4 sub-types
- Classic Kaposi sarcoma 3 trials
- Endemic Kaposi sarcoma 1 trial
- Iatrogenic Kaposi's sarcoma 1 trial
- Colorectal Kaposi sarcoma 0 trials Sub-types →
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Human T-lymphotropic virus 1 infectious disease 5 trials · 34 incl. sub-types
2 sub-types
- Adult T-cell leukemia/lymphoma 31 trials
- Tropical spastic paraparesis 3 trials
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Rabies 27 trials
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Common wart 26 trials
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Vaccinia 17 trials
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Immunodeficiency 32B 9 trials
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Arbovirus infection 8 trials
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Viral eye infection 0 trials · 8 incl. sub-types
5 sub-types
- Herpes simplex virus keratitis 1 trial · 4 incl. sub-types Sub-types →
- Cytomegalovirus retinitis 2 trials
- Viral conjunctivitis 1 trial · 2 incl. sub-types Sub-types →
- Herpes zoster with dermatitis of eyelid 0 trials
- Infectious epithelial keratitis 0 trials
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Human infection by orthopoxvirus 5 trials
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Herpangina 3 trials
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Milker's nodule 3 trials
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Parvoviridae infectious disease 1 trial
2 sub-types
- Aleutian mink disease, human 0 trials
- Fetal parvovirus syndrome 0 trials
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Zika virus congenital syndrome 1 trial
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Molluscum contagiosum 1 trial
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Pharyngoconjunctival fever 1 trial
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Newcastle disease 0 trials
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Reoviridae infectious disease 0 trials
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Whitewater Arroyo hemorrhagic fever 0 trials
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Congenital varicella syndrome 0 trials
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Contagious pustular dermatitis 0 trials
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Epidemic pleurodynia 0 trials
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Exanthema subitum 0 trials
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Focal epithelial hyperplasia 0 trials
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Lumpy skin disease 0 trials
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Neurolymphomatosis 0 trials
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Pseudorabies 0 trials
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Viral esophagitis 0 trials
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Viral gastritis 0 trials
1 sub-type
- Herpetic gastritis 0 trials
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Viral labyrinthitis 0 trials
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Viral myositis 0 trials
Most studied deeper sub-types
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Moderna launches first human test of mRNA vaccine against Epstein-Barr virus
Vaccine OngoingThis early-stage trial is testing an experimental mRNA vaccine called mRNA-1195 to see if it is safe and triggers an immune response against Epstein-Barr virus (EBV). The study involves 482 healthy adults aged 18 to 55, some of whom have had EBV before and some who have not. Part…
Phase 1 • Sponsor: ModernaTX, Inc. • Aim: Vaccine
Last updated Aug 13, 2026 00:00 UTC
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New mRNA shot targets bird flu: 4,000 volunteers needed
Vaccine OngoingThis large phase 3 trial is testing an experimental mRNA vaccine (mRNA-1018-H5) designed to protect against H5N1 pandemic influenza. Around 4,000 healthy adults aged 18 and older will receive two doses of the vaccine or a placebo. Researchers will measure immune responses and mon…
Phase 3 • Sponsor: ModernaTX, Inc. • Aim: Vaccine
Last updated Aug 13, 2026 00:00 UTC
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New mRNA vaccine aims to shield transplant patients from dangerous virus
Vaccine OngoingThis study tests an mRNA vaccine (mRNA-1647) to prevent cytomegalovirus (CMV) infection in people who have had a stem cell transplant. About 84 participants will receive either the vaccine or a placebo. The goal is to see if the vaccine can safely prevent CMV after stopping stand…
Phase 2 • Sponsor: ModernaTX, Inc. • Aim: Vaccine
Last updated Aug 12, 2026 00:00 UTC
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New mRNA vaccine takes aim at RSV in early human trial
Vaccine OngoingThis early-stage trial is testing a new mRNA vaccine called IN006 that targets respiratory syncytial virus (RSV). About 240 healthy adults aged 18 and older will receive either the vaccine or a placebo. The main goal is to check if the vaccine is safe and triggers an immune respo…
Phase 1 • Sponsor: Shenzhen Shenxin Biotechnology Co., Ltd • Aim: Vaccine
Last updated Jun 27, 2026 12:03 UTC
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MRNA HIV vaccine trial launches in healthy volunteers
Vaccine OngoingThis early-stage trial tests whether three experimental mRNA vaccines can safely teach the immune system to recognize and fight HIV. About 108 healthy, HIV-negative adults aged 18-55 will receive one of the vaccines. The main goal is to check for side effects and see if the vacci…
Phase 1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Vaccine
Last updated Jun 27, 2026 07:54 UTC
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New mRNA vaccine aims to shield seniors from RSV
Vaccine OngoingThis study tests a new mRNA vaccine called IN006 against respiratory syncytial virus (RSV) in 500 healthy adults aged 60 and older. The vaccine is given as two different doses, with a booster after 12 or 24 months. Researchers will monitor safety and measure immune responses like…
Phase 2 • Sponsor: Shenzhen Shenxin Biotechnology Co., Ltd • Aim: Vaccine
Last updated Jun 26, 2026 14:29 UTC
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Drug could slash surgeries for rare airway disease
Disease control OngoingThis phase II trial tests whether bevacizumab, a drug that blocks blood vessel growth, can lengthen the time between surgeries for adults with recurrent respiratory papillomatosis (RRP), a rare condition causing wart-like growths in the airways. Participants receive 11 doses of t…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Grandma's secret weapon against colds? mentoring kids may strengthen immunity
Disease control By invitation onlyThis study tests whether a community mentoring program called Generation Xchange (GenX) can help older African-American adults fight off respiratory viruses. 160 participants over age 50 will be randomly assigned to the program or a control group. Researchers will measure immune …
Sponsor: University of California, Los Angeles • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Tailored breathing support may reduce lung injury in ECMO patients
Disease control By invitation onlyThis study tests whether personalized ventilator settings can reduce lung injury in adults with severe respiratory failure who are on ECMO (a heart-lung machine). Researchers will use esophageal manometry or electrical impedance tomography to tailor the ventilator's positive pres…
Sponsor: University of California, San Diego • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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A biologic shot may rewire nasal polyps for years of relief
Disease control OngoingThis trial tests whether mepolizumab, an antibody that blocks a key immune signal, can produce lasting improvements in people with severe nasal polyps. Participants receive twelve monthly injections and are followed for six months after stopping to see if benefits persist. Resear…
Phase 4 • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated Sep 02, 2026 00:00 UTC
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Donor t cells aim to fight severe COVID-19
Disease control OngoingThis early-stage trial tests a therapy made from donor immune cells, called LB-DTK-COV19, in adults with severe COVID-19. The cells are designed to target the virus and are given as a single infusion. The study aims to find a safe dose and see if the treatment can improve symptom…
Phase 1 • Sponsor: LucasBio • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Can cord blood t cells be trained to stop viral infections after transplant?
Disease control OngoingThis trial is testing whether specially grown T cells from cord blood can help prevent or treat infections caused by common viruses (CMV, EBV, BKV, and adenovirus) in people who have had a cord blood transplant. The study aims to find the safest and most effective dose of these v…
Phase 1/2 • Sponsor: Catherine Bollard • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Lab-grown immune cells take on seven viruses in transplant patients
Disease control OngoingThis early-stage study tests whether immune cells grown from a donor's blood can safely fight or prevent seven different viruses in people who have had a bone marrow transplant. About 32 participants will receive these cells either as a preventive measure or as a treatment for ac…
Phase 1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Experimental virus therapy for childhood brain tumors tested with radiation
Disease control CancelledThis study aimed to test an experimental virus therapy called G207, combined with a single dose of radiation, in children whose high-grade glioma had come back after prior treatment. The virus was injected directly into the brain tumor to kill cancer cells and trigger an immune r…
Phase 2 • Sponsor: Pediatric Brain Tumor Consortium • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Supercharged immune cells take on post-transplant viruses
Disease control OngoingThis study tests a new way to treat viral infections that often occur after a solid organ transplant. Researchers create special immune cells, called viral-specific T-cells, from the patient's own blood to fight the virus. The goal is to reduce the need for strong anti-viral drug…
Phase 2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Gene-Edited stem cells aim to tame HIV
Disease control OngoingThis study tests whether giving HIV patients their own genetically modified stem cells is safe and feasible. The cells are changed to resist HIV, and patients receive a mild chemotherapy drug before infusion. The goal is to see if the modified cells can help control the virus, bu…
Phase 1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Engineered virus takes on deadly brain cancer
Disease control OngoingThis early-stage trial tests a single dose of M032, a genetically modified herpes simplex virus that produces IL-12, in 29 patients with recurrent or progressive brain tumors (glioblastoma, anaplastic astrocytoma, or gliosarcoma). The virus is infused directly into the tumor area…
Phase 1 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New rapid test could slash unnecessary antibiotic use in emergency rooms
Diagnosis OngoingThis study tests a fast point-of-care PCR test (Spotfire) that quickly identifies whether a respiratory infection is caused by a virus. The goal is to give ER doctors results faster so they can avoid prescribing antibiotics when they won't help. The trial enrolls 200 adults with …
Sponsor: Christopher Payette • Aim: Diagnosis
Last updated Jun 27, 2026 07:58 UTC
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Robotic surgery or radiation? new study compares which is better for throat cancer patients' quality of life
Symptom relief OngoingThis study compares two treatments for early-stage throat cancer: robotic surgery (TORS) or radiation therapy (IMRT). It looks at which one leads to better swallowing function and overall quality of life. About 138 adults with HPV-related throat cancer are taking part. The goal i…
Sponsor: Christian von Buchwald • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Bird flu rechallenge: scientists Re-Infect volunteers to unlock immune secrets
Knowledge-focused By invitation onlyThis study aims to understand how the immune system responds to a second infection with a mild bird flu virus (H10N7). Healthy adults who were infected with H10N7 in a previous study will be infected again and monitored closely in the hospital for 9 days. The goal is to learn mor…
Phase 1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Sep 11, 2026 00:00 UTC
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Scientists compare immune responses to viral and bacterial infections in ICU patients
Knowledge-focused OngoingThis study looks at how the immune system of patients in the intensive care unit (ICU) responds to severe infections caused by viruses or bacteria. Researchers will take extra blood samples from 38 adults to analyze immature granulocytes, a type of immune cell. The goal is to see…
Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Thousands monitored for vaccine side effects in korean safety study
Knowledge-focused OngoingThis study tracks over 4,200 people in South Korea who received a SPIKEVAX COVID-19 vaccine to see if any side effects occur over time. Participants are aged 12 or older depending on the vaccine version. The goal is to gather real-world safety data, not to test if the vaccine wor…
Sponsor: ModernaTX, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Could viruses and epigenetics be the hidden cause of chronic sinusitis?
Knowledge-focused OngoingThis study investigates why some people develop chronic sinusitis with nasal polyps, focusing on how epigenetic changes and viruses might trigger the disease. Researchers will analyze tissue samples from 60 participants, including patients with active disease, those in remission,…
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Massive review of viral meningitis cases aims to sharpen diagnosis
Knowledge-focused OngoingThis study looks back at 4000 patients who had a suspected viral infection of the brain or spinal cord. Researchers will analyze which viruses were found and how the illness progressed in different groups, including children, adults, and people with weakened immune systems. The g…
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Scientists probe how long monkeypox vaccine immunity lasts
Knowledge-focused OngoingThis study looks at how long the JYNNEOS vaccine protects people from smallpox and monkeypox. Researchers will measure immune responses in the blood, lungs, skin, and bone marrow of 20 healthy adults who receive the vaccine. The goal is to understand the durability of protection,…
Early phase 1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC