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Could mRNA technology finally tackle HIV? new trial launches

NCT ID NCT05217641

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 28 times

Summary

This early-stage study tests three experimental mRNA vaccines designed to teach the body to fight HIV. About 108 healthy, HIV-negative adults aged 18-55 will receive the vaccines to check for safety and whether they produce protective antibodies. The goal is to see if these vaccines are safe and trigger an immune response against HIV.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alabama CRS [31788]

    Birmingham, Alabama, 35222, United States

  • Bidmc Vcrs [32077]

    Boston, Massachusetts, 02115, United States

  • Brigham and Women's Hospital Vaccine CRS [30007]

    Boston, Massachusetts, 02115, United States

  • Columbia P&S CRS [30329]

    New York, New York, 30329, United States

  • New York Blood Center CRS [31801]

    New York, New York, 10065, United States

  • Penn Prevention CRS [30310]

    Philadelphia, Pennsylvania, 19104, United States

  • Seattle Vaccine and Prevention CRS [30331]

    Seattle, Washington, 98104, United States

  • UCLA Vine Street Clinic CRS [31607]

    Los Angeles, California, 90038, United States

  • University of Pittsburgh CRS [1001]

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Rochester Vaccines to Prevent HIV Infection CRS [31467]

    Rochester, New York, 14642, United States

Conditions

Explore the condition pages connected to this study.