Sleep apnea syndrome

This study tests a culturally tailored sleep program for Latino couples where one partner has sleep apnea and is starting CPAP therapy. The program includes three telehealth sessions teaching sleep skills and support strategies. Researchers want to see if it improves CPAP use and…

This study tests whether using a CPAP machine to treat sleep apnea shortly after an ischemic stroke can reduce the risk of another stroke, heart attack, or death within 6 months. It also looks at whether CPAP improves overall recovery and brain function. Over 3,000 participants a…

This study looks at whether using a CPAP machine at night can reduce the chance of atrial fibrillation (an irregular heartbeat) returning in people who have both sleep apnea and a history of AF. Researchers will follow 91 adults for 12 months, tracking how often they use CPAP and…

This study tests whether a time-efficient breathing exercise program can help lower blood pressure in adults aged 50 and older who have moderate to severe sleep apnea but cannot or will not use a CPAP machine. Researchers will measure blood pressure changes over 36 weeks in 122 p…

This study is testing whether a wearable ring and a small body sensor can accurately diagnose sleep-disordered breathing, including sleep apnea. About 79 adults with suspected sleep apnea will wear the devices during an overnight sleep lab test. The goal is to see if the ring's r…

This study planned to test a new wearable wireless device that wraps around a child's abdomen to monitor central sleep apnea. It would have involved 15 children aged 1 month to 5 years already undergoing standard sleep studies. The device's accuracy and comfort would have been co…

This study tests whether Withings bathroom scales can accurately measure pulse wave velocity (PWV), a key indicator of vascular stiffness. Researchers will compare readings from the scales with a standard medical device in 176 adults, including those with high blood pressure, sle…

This study checks if a Withings smartwatch can accurately detect sleep apnea compared to a full hospital sleep test. About 220 adults who are already scheduled for a sleep test will wear the watch overnight. The goal is to see if the watch can help screen more people for sleep ap…

This study tests whether a non-contact device placed under the mattress can accurately detect sleep apnea. Researchers will compare the device's readings to standard sleep tests in 200 adults suspected of having sleep apnea. If proven reliable, this could offer a simple, low-cost…

This study looks at whether adding CPAP (a machine that helps you breathe at night) to a healthy lifestyle program can lower the risk of diabetes in people with prediabetes and sleep apnea. About 174 overweight or obese adults with both conditions will be followed for 6 months. T…

This study tests whether drinking a ketone supplement (Ketone-IQ) before sleep can improve sleep quality and reduce breathing pauses in people with moderate-to-severe obstructive sleep apnea. Thirty adults who already use CPAP will try the ketone drink for two nights and a placeb…

This study tests whether drinking a ketone supplement (Ketone-IQ) before bed can improve sleep quality and reduce sleep apnea severity in 30 adults who already use a CPAP machine. Participants will try two different doses and compare effects to a placebo. The goal is to find a si…

This study aimed to see if taking branched-chain amino acids (BCAAs) could improve oxygen levels during sleep in people with sleep apnea. The researchers planned to include adults with confirmed sleep apnea but exclude those with severe cases. However, the study was withdrawn bef…

This Phase 2A study tests three drugs—sivopixant, acetazolamide, and SASS-001—in 60 adults with sleep apnea that has a central component (where the brain fails to signal breathing). The goal is to see if these drugs can reduce the number of breathing pauses during sleep. Particip…

This study aimed to see if an educational game called Yapouni could help children aged 3 to 16 use their CPAP or NIV breathing machines more consistently. The game was designed to motivate children by linking machine use to a hot air balloon's flight. However, the study was withd…

This study tests whether doing simple mouth, tongue, and throat exercises using a mobile app can improve snoring and sleep apnea better than following a paper guide. The 34 participants are adults with mild to severe obstructive sleep apnea who could not or would not use a CPAP m…

This study tests whether showing people with sleep apnea how their CPAP machine use compares to other patients helps them use it more consistently. About 186 adults who have been on CPAP for at least three months will be split into two groups: one gets routine feedback on their o…

This study looks at whether dopamine levels and certain genes affect the risk and severity of sleep breathing disorders like sleep apnea. Researchers will monitor 100 adults overnight and take blood samples to measure dopamine and check for genetic variations. The goal is to bett…

This study aims to find out how often sleep apnea occurs in pregnant women and what factors might increase the risk. Researchers will invite pregnant women to undergo a sleep test called polysomnography during their first two trimesters. The goal is to better understand this cond…

This study follows 2,000 adults aged 45-75 in Pennsylvania to better understand why some groups have higher heart disease risk. About 800 participants at higher risk will receive either usual care or a personalized program with nutrition, exercise, and stress management advice. T…

This study will survey directors of dental programs at Italian universities to find out if sleep medicine is part of the curriculum. The goal is to understand how much future dentists learn about sleep-disordered breathing like sleep apnea. About 70 program directors will answer …

This study looks at why sleep apnea raises the risk of diabetes. Overweight adults with and without sleep apnea will have their blood sugar control measured. Some will receive CPAP, some will get extra oxygen at night, and others will get a sham treatment. The goal is to find out…

This study looks at how sleep apnea might cause prediabetes to turn into diabetes. Researchers will use CPAP machines and niacin infusions in 300 overweight, prediabetic adults with sleep apnea to measure changes in blood chemicals. The goal is to understand the biological steps …

This study looks at how age-related sleep changes and sleep apnea might increase the risk of Alzheimer's disease. Researchers will use brain scans and overnight sleep tests in 158 healthy adults aged 55-75 to measure amyloid buildup and sleep patterns over two years. The goal is …

This study uses a 30-40 minute online survey to understand how being on call affects sleep in 1,000 medical trainees (students, residents, fellows). It looks at sleep quality, quantity, and disruption to body rhythms. The goal is to gather knowledge to improve sleep health for he…

This study examines the links between sleep bruxism (teeth grinding during sleep) and sleep quality, heart health, thyroid function, and mood. Researchers will give some participants opipramol, a drug that may reduce grinding activity, and monitor them with sleep tests. The goal …

This study looks at whether sleep-disordered breathing, like obstructive sleep apnea, is linked to worsening spine curves in children with idiopathic scoliosis. Researchers will follow 405 children aged 6 to 15 with mild to moderate scoliosis. They will measure spine curves and s…

This study aimed to see if giving extra oxygen at night could improve blood sugar control in people living at high altitudes who have sleep-disordered breathing. It was designed for permanent residents of Puno, Peru, but was withdrawn before any participants were enrolled. No res…

This study collects blood, urine, and tissue samples from 500 obese adults to help researchers understand why people gain weight, lose weight, or regain weight after treatment. Participants must be over 18 with a BMI of 30 or higher. The samples will be stored for up to 10 years …

This study looks at how sleep problems like apnea, insomnia, and poor sleep quality are linked to heart disease and diabetes in rural southern areas. About 3,680 adults already in a larger health study will wear sleep trackers and answer questionnaires. The goal is to understand …

This study follows 1,545 adults over many years to understand how sleep-disordered breathing and other sleep problems develop and affect health. Participants were Wisconsin state employees aged 30-60 when the study began. Researchers use overnight sleep tests, questionnaires, and…

This study looks at sleep quality in 60 adults with non-cystic fibrosis bronchiectasis, a chronic lung condition. Researchers will measure how well participants sleep and see if poor sleep is linked to more severe lung disease, worse breathing tests, or more lung damage on CT sca…