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Reproductive system disorder
MONDO:0005039A disease involving the reproductive system.
Also known as: disease of reproductive system, disease or disorder of reproductive system, disorder of reproductive system, genital disorders, reproductive disease, reproductive system disease, reproductive system disease or disorder, reproductive system disorder
8559 clinical trials for this condition and its sub-types, 15 tagged with Reproductive system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Reproductive system disorder
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Reproductive system neoplasm 0 trials · 4,662 incl. sub-types
9 sub-types
- Reproductive system cancer 4 trials · 4,391 incl. sub-types Sub-types →
- Female reproductive system neoplasm 27 trials · 2,431 incl. sub-types Sub-types →
- Male reproductive system neoplasm 1 trial · 2,378 incl. sub-types Sub-types →
- Prostate neoplasm 126 trials · 2,233 incl. sub-types Sub-types →
- Benign reproductive system neoplasm 0 trials · 117 incl. sub-types Sub-types →
- Pituitary tumor 23 trials · 83 incl. sub-types Sub-types →
- Sex cord-stromal tumor 4 trials · 14 incl. sub-types Sub-types →
- Brenner tumor 6 trials Sub-types →
- Gonadal tissue neoplasm 0 trials
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Female reproductive system disorder 27 trials · 3,577 incl. sub-types
34 sub-types
- Female reproductive system neoplasm 27 trials · 2,431 incl. sub-types Sub-types →
- Uterine disorder 18 trials · 1,925 incl. sub-types Sub-types →
- Ovarian disorder 10 trials · 1,391 incl. sub-types Sub-types →
- Fallopian tube disorder 5 trials · 428 incl. sub-types Sub-types →
- Menstrual disorder 16 trials · 192 incl. sub-types Sub-types →
- Vaginal disorder 3 trials · 174 incl. sub-types Sub-types →
- Female infertility 107 trials · 162 incl. sub-types Sub-types →
- Vulvar disease 8 trials · 154 incl. sub-types Sub-types →
- Preterm premature rupture of the membranes 35 trials
- Prolapse of female genital organ 32 trials · 35 incl. sub-types Sub-types →
- Asherman syndrome 19 trials
- Gynatresia 18 trials
- Vulvodynia 18 trials
- Ectopic pregnancy 15 trials Sub-types →
- Pelvic inflammatory disease 4 trials · 14 incl. sub-types Sub-types →
- Mullerian aplasia 9 trials · 10 incl. sub-types Sub-types →
- Granulomatous mastitis 6 trials
- Delayed puberty, self-limited 3 trials
- Allen-Masters syndrome 0 trials
- Bartholin duct cyst 0 trials
- Bartholin's gland disease 0 trials
- Endosalpingiosis 0 trials Sub-types →
- Hymen, imperforate 0 trials
- Isolated partial vaginal agenesis 0 trials
- Longitudinal vaginal septum 0 trials
- Mammary-digital-nail syndrome 0 trials
- Menstrual cycle-dependent periodic fever 0 trials
- Polycystic ovaries-urethral sphincter dysfunction syndrome 0 trials
- Polyp of vulva 0 trials Sub-types →
- Transverse vaginal septum 0 trials
- Uterine cervical aplasia and agenesis 0 trials
- Vaginal atresia 0 trials
- Vulval varices 0 trials
- Vulvovaginal gingival syndrome 0 trials
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Male reproductive system disorder 11 trials · 2,836 incl. sub-types
26 sub-types
- Prostate disorder 16 trials · 2,448 incl. sub-types Sub-types →
- Male reproductive system neoplasm 1 trial · 2,378 incl. sub-types Sub-types →
- Penile disorder 3 trials · 195 incl. sub-types Sub-types →
- Testicular disorder 2 trials · 111 incl. sub-types Sub-types →
- Male infertility 74 trials · 92 incl. sub-types Sub-types →
- Scrotal disorder 2 trials · 19 incl. sub-types Sub-types →
- Cryptorchidism 14 trials Sub-types →
- Hydrocele 6 trials Sub-types →
- Epididymitis 2 trials Sub-types →
- Fournier gangrene 2 trials
- Congenital bilateral absence of vas deferens 1 trial Sub-types →
- Hematocele of tunica vaginalis testis 1 trial
- Isolated micropenis 1 trial
- Spermatocele 1 trial
- Benign male reproductive system neoplasm 0 trials Sub-types →
- Congenital agenesis of the scrotum 0 trials
- Congenital megaprepuce 0 trials
- Dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome 0 trials
- Diphallia 0 trials
- Epididymis disease 0 trials
- Male genital organ stricture 0 trials
- Male genital organ vascular disease 0 trials
- Male genital tuberculosis 0 trials Sub-types →
- Penoscrotal transposition 0 trials
- Posterior hypospadias 0 trials
- Postorgasmic illness syndrome 0 trials
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Sexually transmitted disease 127 trials · 1,708 incl. sub-types
3 sub-types
- Viral sexually transmitted disease 5 trials · 1,593 incl. sub-types Sub-types →
- Bacterial sexually transmitted disease 8 trials · 114 incl. sub-types Sub-types →
- Trichomonas vaginitis urogenital infection 7 trials Sub-types →
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Gonadal disorder 3 trials · 1,639 incl. sub-types
6 sub-types
- Ovarian disorder 10 trials · 1,391 incl. sub-types Sub-types →
- Hypogonadism 47 trials · 164 incl. sub-types Sub-types →
- Testicular disorder 2 trials · 111 incl. sub-types Sub-types →
- Disorder of sexual differentiation 9 trials · 55 incl. sub-types Sub-types →
- Precocious puberty 18 trials · 19 incl. sub-types Sub-types →
- Gonadoblastoma 0 trials Sub-types →
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Infertility disorder 361 trials · 545 incl. sub-types
5 sub-types
- Female infertility 107 trials · 162 incl. sub-types Sub-types →
- Male infertility 74 trials · 92 incl. sub-types Sub-types →
- Pregnancy loss, recurrent, 4 14 trials
- SYCE1-related gametogenic failure 0 trials Sub-types →
- Inherited oocyte maturation defect 0 trials Sub-types →
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Physiological sexual disorder 79 trials · 199 incl. sub-types
1 sub-type
- Erectile dysfunction 122 trials · 126 incl. sub-types Sub-types →
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Pituitary gland disorder 18 trials · 175 incl. sub-types
9 sub-types
- Pituitary tumor 23 trials · 83 incl. sub-types Sub-types →
- Anterior pituitary gland disorder 1 trial · 60 incl. sub-types Sub-types →
- Hypopituitarism 5 trials · 46 incl. sub-types Sub-types →
- Neurohypophyseal diabetes insipidus 9 trials
- Inappropriate ADH syndrome 5 trials
- Hypophysitis 2 trials Sub-types →
- Necrosis of pituitary 0 trials · 1 incl. sub-types Sub-types →
- Empty sella syndrome 0 trials
- Pituitary hypoplasia 0 trials
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Pelvic organ prolapse 125 trials
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Dysplasia of cervix 55 trials · 105 incl. sub-types
1 sub-type
- Cervical intraepithelial neoplasia 75 trials · 104 incl. sub-types Sub-types →
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Hypospadias 35 trials
5 sub-types
- Hypospadias 1, X-linked 0 trials
- Hypospadias 2, X-linked 0 trials
- Hypospadias 3, autosomal 0 trials
- Hypospadias 4, X-linked 0 trials
- Isolated female hypospadias 0 trials
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Habitual spontaneous abortion 28 trials
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Currarino triad 1 trial
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4 sub-types
- 46,XX sex reversal 4 0 trials
- 46,XY sex reversal 3 0 trials
- Premature ovarian failure 7 0 trials
- Spermatogenic failure 8 0 trials
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Aromatase excess syndrome 0 trials
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Cortisone reductase deficiency 0 trials
2 sub-types
- Cortisone reductase deficiency 1 0 trials
- Cortisone reductase deficiency 2 0 trials
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Diethylstilbestrol syndrome 0 trials
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Estrogen resistance syndrome 0 trials
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Female genital tuberculosis 0 trials
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Hand-foot-genital syndrome 0 trials
Most studied deeper sub-types
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Scientists hunt for genes that control puberty
Knowledge-focused CompletedThis study aims to find the genes involved in inherited reproductive disorders, such as delayed or early puberty and low hormone levels. Researchers will analyze genetic data from 600 participants with these conditions. The goal is to identify genetic variations that may explain …
Sponsor: Stephanie B. Seminara, MD • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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New imaging database aims to improve endometriosis diagnosis
Knowledge-focused CompletedThis study collected ultrasound and MRI images from 100 women with endometriosis who were scheduled for surgery. The goal was to create a database that helps doctors better identify and stage the disease using these scans. Participants were aged 18-40, had a clinical diagnosis, a…
Sponsor: Perspectum • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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New tool measures the Real-Life impact of vaginal aging in portuguese women
Knowledge-focused CompletedThis study tested a Portuguese version of the DIVA questionnaire to see if it reliably measures how vaginal aging symptoms (like dryness, itching, or pain) affect daily activities, sex life, emotions, and body image. 300 women with at least one symptom of vulvovaginal atrophy too…
Sponsor: Instituto Politécnico de Leiria • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Can we fix genetic counseling? new study says yes!
Knowledge-focused CompletedThis study tested new ways to make genetic counseling more helpful for people from all backgrounds. Over 1,000 adults completed surveys and allowed their counseling sessions to be recorded. The goal was to see if different counseling methods lead to better experiences, especially…
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Opioid blocker trial probes hormone secrets in biobank volunteers
Knowledge-focused CompletedThis completed Phase 1 study looked at how naloxone, an opioid blocker, affects reproductive hormones in 47 healthy adults. Participants had genetic data available from the Mass General Brigham Biobank. Researchers measured changes in luteinizing hormone pulses before and during …
Phase 1 • Sponsor: Stephanie B. Seminara, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Can a hormone infusion tame PCOS? early study hints at possibility
Knowledge-focused CompletedThis early study tested whether giving a continuous infusion of kisspeptin, a natural hormone, could dampen the overactive reproductive signals seen in polycystic ovary syndrome (PCOS). Eight women with PCOS received the hormone for 24 hours, and researchers measured changes in t…
Phase 1 • Sponsor: Stephanie B. Seminara, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC