Mental disorder

This trial tests a six-session peer-led program called Gwan Enjoy Life for sexual minority men living with HIV in Jamaica. The program aims to reduce depression, anxiety, and loneliness while helping participants stay engaged in HIV care and take their medications. Sixty men will…

This study looks at whether a program called EMPOWER, led by trained peer supporters, can help homeless veterans with substance use or mental health issues stay engaged in care and avoid repeated hospital stays or emergency visits. About 278 veterans in permanent supportive housi…

This study looks at whether an online education and support program can help people with schizophrenia or bipolar disorder stick to their medication plans. Researchers will compare digital questionnaires with pharmacy records to measure adherence. About 1,640 adults in Spain will…

This study looks at whether extra education from a pharmacist can help people aged 18-60 who are starting a new antipsychotic medication for conditions like schizophrenia or bipolar disorder. The goal is to see if this support reduces weight gain and other metabolic side effects.…

This trial tests whether a collaborative psychological model—combining daily music listening, a smartphone app with AI chatbot support and mindfulness exercises, telephone check-ins, and wearable monitoring—can reduce the risk of postnatal depression and persistent pain after chi…

This study tests a WeChat mini-program that sends heat warnings to parents and teachers of 200 fourth-graders in Beijing. When temperatures reach risky levels, the program shares health tips and alerts. The goal is to see if this helps children stay physically healthy and think c…

This study tests a 24-week school program to prevent myopia, obesity, and mental health problems in children aged 8-11. The program includes animated videos, family activities, and health lessons. Researchers will compare these kids to those receiving standard health education, t…

This study tests a telephone program where older adults in rural areas share life memories three times a week. Researchers want to see if it reduces loneliness and improves mental well-being, social support, and life satisfaction for both older adults and their informal caregiver…

This study tests a program called Enlace Familiar, designed to help Latino teenagers ages 14-18 talk about their mental health with parents or trusted adults. The program involves two sessions with a community health worker and a list of mental health resources. Researchers want …

This study tests whether adults with chronic, stable mental health conditions will actively engage in a 4-month musical immersion program called Résonance(s), which includes rehearsals with a professional orchestra, listening sessions, and a final public concert. The main questio…

This pilot study tests a new model of mental health support for siblings aged 10-17 of children with medical complexity. The model uses screening and assessments by social workers, who can provide talk therapy or refer to a child psychiatrist for diagnosis and treatment. The goal…

This trial tests whether Narrative Enhancement and Cognitive Therapy (NECT), a 12-session group program, can help adults with severe mental health disorders — including substance use disorders — overcome self-stigma and promote personal recovery. About 106 participants receiving …

This trial tests whether a 6-week online program delivered via WeChat or WhatsApp can help pregnant women and their partners sleep better and feel less stressed. The program includes videos, quizzes, and professional support. Researchers will measure sleep quality, heart rate, an…

This pilot study explores whether group workshops using MaKey MaKey and Scratch—tools that turn everyday objects into touchpads for creating music, games, and stories—can improve social participation, motivation, and empowerment in adults with mental health conditions. Twenty par…

This study tests whether short virtual reality nature sessions can lower stress for people admitted to an acute psychiatric ward. 120 adult patients will either receive standard care or add 10-15 minute VR nature experiences every other day. Researchers will measure changes in pe…

This study tests whether a combination of real-time brain training (using a wearable brain scanner called fNIRS) and personalized text messages can help women with bulimia nervosa improve self-control and reduce binge eating. Forty women aged 18-55 will receive either real or sha…

This study tests a single 90-minute therapy session for teens aged 13-18 who have experienced trauma and are waiting for longer treatment. The session teaches coping skills and understanding of trauma cues. About 40 teens in New Zealand will take part to see if this approach is p…

This study looks at whether offering bereavement counselling to parents who have lost a baby (after 16 weeks of pregnancy or shortly after birth) is practical and helpful. About 26 parents will either receive usual hospital bereavement care or get extra counselling. Researchers w…

This study tests a 15-session group therapy program for people with schizophrenia who still hear voices despite medication. The program combines several proven strategies to help reduce how often the voices occur and how much distress they cause. Researchers will compare the ther…

This study tests a program that combines doctor care, digital tools, virtual reality, and school-based support to help teens and adults in Morocco with depression and anxiety. About 146 participants will be split into two groups: one gets the new program, the other gets usual car…

This natural history study will explore how life experiences and environmental factors affect heart health and metabolism among 50 Bhutanese adults living in the US. Participants will complete a survey and discuss their views on providing biological samples. The goal is to identi…

This study tests a mobile health program called SAMU to help adults in Uganda who have HIV, high blood pressure, and mental health issues like depression or anxiety. About 1,500 participants will use their phones for mental health screening and get connected to care. The goal is …

This study investigates how the brain processes social decisions like trust and cooperation. Participants play a modified trust game, either in an MRI scanner or online, where their choices affect monetary gains or losses. The goal is to link brain activity and behavior to person…

This study looks at the nutritional health of people aged 65 and older who are hospitalized with mental disorders. Researchers will assess conditions like malnutrition, frailty, and obesity, and use the findings to design a practical care pathway for nutritional support. The goal…

This study follows 2,000 adults with severe mental illness (such as schizophrenia, bipolar disorder, or severe depression) who are admitted to intensive care units (ICUs) in France. Researchers track their survival and other outcomes for up to 12 months to identify factors that p…

This study tests a new program called CapExchange, where people with stable mental health conditions exchange practical skills with others in their community. The goal is to see if this approach is practical and helpful for improving well-being and social connection. About 10 to …

This study will test a tool called the Health Improvement Profile (HIP) in a mental health inpatient unit. The HIP is a checklist that helps clinicians spot physical health problems like high blood pressure or poor diet in people being treated for mental illness. Researchers will…

This study looks at 125 hospitalized adults who have both a mental disorder and a substance use problem (dual diagnosis). Researchers want to see if things like social support and coping skills are linked to better treatment adherence and daily functioning. The goal is to find pr…

This study looks at how people with a first episode of psychosis tell their life stories and whether that relates to their well-being and recovery. Researchers will compare 96 participants—those with early psychosis, those with chronic psychosis, and healthy controls—using questi…