Common cold

This trial compares three FDA-cleared in-office procedures that treat chronic non-allergic rhinitis by targeting the posterior nasal nerve. Radiofrequency ablation (using RhinAer or Neuromark) uses heat, while cryoablation (ClariFix) uses extreme cold to reduce nerve signals that…

This study tests a fast point-of-care PCR test (Spotfire) that quickly identifies whether a respiratory infection is caused by a virus. The goal is to give ER doctors results faster so they can avoid prescribing antibiotics when they won't help. The trial enrolls 200 adults with …

This study tests whether simple, low-cost air cleaning devices—box fans with filters and ultraviolet light lamps—placed in classrooms can reduce how often schoolchildren catch respiratory viruses like flu and COVID-19. Researchers will compare illness rates among children in clas…

This study tests a propolis throat spray to see if it can reduce how often and how long healthy adults get sick. One hundred people aged 18 to 65 will use the spray or a placebo daily for 16 weeks and report any illnesses. The goal is to find a simple way to prevent common colds …

This study tests a procedure called RhinAer that uses heat to treat the nerves in the nose for people with chronic rhinitis (long-term stuffy or runny nose). Researchers want to see if it reduces inflammation and improves symptoms like cough and post-nasal drip. About 25 adults a…

This study looks at how the immune system of patients in the intensive care unit (ICU) responds to severe infections caused by viruses or bacteria. Researchers will take extra blood samples from 38 adults to analyze immature granulocytes, a type of immune cell. The goal is to see…

This study looks at whether air samplers placed in homes can detect viruses that cause colds and flu, and how that compares to standard nasal swabs. About 422 students and their families will participate. The goal is to better understand how respiratory viruses spread through hou…

This pilot study is testing whether two natural dietary supplements—taxifolin (found in apples and onions) and ergothioneine (found in mushrooms)—can improve immune function in healthy adults aged 50 to 65. Researchers will measure how well immune cells engulf and destroy threats…

This study compares new, less invasive ways to collect samples for respiratory virus testing—like a nasal wash or saliva—against the standard deep nose swab. Researchers want to see if these gentler methods work just as well and cause less pain. About 1,000 adults in the emergenc…

This study places a rapid testing device in primary care clinics to help doctors quickly identify whether a cold-like illness is caused by a virus or bacteria. About 8,000 adults with symptoms like cough or runny nose will get a nasal swab, with results in 15 minutes. The goal is…