Cardiovascular disorder
MONDO:0004995A disease involving the cardiovascular system.
Also known as: cardiovascular disease, cardiovascular disease (CVD), cardiovascular disorder, cardiovascular system disease, cardiovascular system disease or disorder, disease of cardiovascular system, disease or disorder of cardiovascular system, disorder of cardiovascular system
15366 clinical trials for this condition and its sub-types, 1115 tagged with Cardiovascular disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Cardiovascular disorder
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Vascular disorder 141 trials · 10,696 incl. sub-types
60 sub-types
- Arterial disorder 11 trials · 5,313 incl. sub-types Sub-types →
- Neurovascular disorder 5 trials · 4,196 incl. sub-types Sub-types →
- Ischemic disease 61 trials · 933 incl. sub-types Sub-types →
- Peripheral vascular disease 57 trials · 432 incl. sub-types Sub-types →
- Ocular vascular disorder 0 trials · 349 incl. sub-types Sub-types →
- Vein disorder 15 trials · 324 incl. sub-types Sub-types →
- Vasculitis 63 trials · 286 incl. sub-types Sub-types →
- Blood vessel neoplasm 0 trials · 254 incl. sub-types Sub-types →
- Vascular insufficiency disorder 1 trial · 244 incl. sub-types Sub-types →
- Venous thromboembolism 240 trials
- Thrombotic disease 177 trials · 222 incl. sub-types Sub-types →
- Vascular occlusion disorder 27 trials · 182 incl. sub-types Sub-types →
- Skin vascular disease 5 trials · 134 incl. sub-types Sub-types →
- Hepatic vascular disorder 1 trial · 116 incl. sub-types Sub-types →
- Coronary microvascular disorder 69 trials
- Vascular ectasia 4 trials · 67 incl. sub-types Sub-types →
- Vascular hemostatic disease 62 trials · 63 incl. sub-types Sub-types →
- Lymphatic malformation 17 trials · 55 incl. sub-types Sub-types →
- Capillary malformation 4 trials · 49 incl. sub-types Sub-types →
- Vascular malformation 32 trials · 34 incl. sub-types Sub-types →
- Patent ductus arteriosus 28 trials Sub-types →
- Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 16 trials · 19 incl. sub-types Sub-types →
- Idiopathic spontaneous coronary artery dissection 15 trials
- Lymphatic vessel neoplasm 0 trials · 15 incl. sub-types Sub-types →
- Familial thoracic aortic aneurysm and aortic dissection 11 trials · 12 incl. sub-types Sub-types →
- Thoracic outlet syndrome 11 trials Sub-types →
- Calciphylaxis 9 trials Sub-types →
- Arterial calcification of infancy 7 trials Sub-types →
- Ehlers-Danlos syndrome, vascular type 6 trials Sub-types →
- Loeys-Dietz syndrome 6 trials Sub-types →
- Angioosteohypertrophic syndrome 6 trials
- Capillary disorder 0 trials · 4 incl. sub-types Sub-types →
- Congenital portosystemic shunt 4 trials Sub-types →
- Angiodysplasia 2 trials · 3 incl. sub-types Sub-types →
- STING-associated vasculopathy with onset in infancy 2 trials
- Multisystemic smooth muscle dysfunction syndrome 2 trials Sub-types →
- Superior vena cava syndrome 2 trials
- Bannayan-Riley-Ruvalcaba syndrome 1 trial
- Arterial tortuosity syndrome 1 trial
- Congenital anomaly of the inferior vena cava 1 trial Sub-types →
- Hereditary arterial and articular multiple calcification syndrome 1 trial
- Multiple cutaneous and mucosal venous malformations 1 trial
- Ehlers-Danlos syndrome, vascular-like type 0 trials
- Arterial dissection-lentiginosis syndrome 0 trials
- Arterial tortuosity-bone fragility syndrome 0 trials
- Bleeding disorder, vascular-type 0 trials
- Cholesterol embolism 0 trials Sub-types →
- Congenital anomaly of hepatic vein 0 trials
- Congenital anomaly of superior vena cava 0 trials Sub-types →
- Congenital renal artery stenosis 0 trials
- Coronary sinus atresia 0 trials
- Coronary sinus stenosis 0 trials
- Fibrocartilaginous embolism 0 trials
- Internal carotid agenesis 0 trials
- Ischemic colitis 0 trials
- Lethal arteriopathy syndrome due to fibulin-4 deficiency 0 trials
- Neonatal Marfan syndrome 0 trials
- Pulmonary venoocclusive disease 0 trials Sub-types →
- Segmental arterial mediolysis 0 trials
- Vascular disorder of penis 0 trials
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Heart disorder 310 trials · 6,754 incl. sub-types
34 sub-types
- Heart failure 1,349 trials · 1,674 incl. sub-types Sub-types →
- Cardiac rhythm disease 173 trials · 1,515 incl. sub-types Sub-types →
- Coronary artery disorder 1,261 trials · 1,403 incl. sub-types Sub-types →
- Myocardial disorder 5 trials · 1,062 incl. sub-types Sub-types →
- Cardiomyopathy 155 trials · 819 incl. sub-types Sub-types →
- Heart valve disorder 181 trials · 769 incl. sub-types Sub-types →
- Cardiogenetic disease 3 trials · 614 incl. sub-types Sub-types →
- Congenital heart disease 266 trials · 416 incl. sub-types Sub-types →
- Cardiac ventricle disorder 4 trials · 406 incl. sub-types Sub-types →
- Heart conduction disease 7 trials · 176 incl. sub-types Sub-types →
- Inflammation of heart layer 1 trial · 114 incl. sub-types Sub-types →
- Cardiogenic shock 100 trials
- Coronary microvascular disorder 69 trials
- Endocardium disorder 0 trials · 61 incl. sub-types Sub-types →
- Pericardium disorder 2 trials · 36 incl. sub-types Sub-types →
- Rheumatic heart disease 17 trials Sub-types →
- 22q11.2 deletion syndrome 7 trials · 13 incl. sub-types Sub-types →
- Heart neoplasm 3 trials · 7 incl. sub-types Sub-types →
- Hypertensive heart disease 7 trials
- PHACE syndrome 2 trials
- Carcinoid heart disease 2 trials
- Aortopulmonary window 1 trial
- Heart aneurysm 1 trial
- Myocardial rupture 1 trial
- Thomas syndrome 0 trials
- Atrioventricular defect-blepharophimosis-radial and anal defect syndrome 0 trials
- Cardiac anomalies-heterotaxy syndrome 0 trials
- Cardiac tuberculosis 0 trials
- Cor biloculare 0 trials
- Microcephaly-cardiac defect-lung malsegmentation syndrome 0 trials
- Microcephaly-facio-cardio-skeletal syndrome, Hadziselimovic type 0 trials
- Omphalocele-diaphragmatic hernia-cardiovascular anomalies-radial ray defect syndrome 0 trials
- Polyvalvular heart disease syndrome 0 trials Sub-types →
- White forelock with malformations 0 trials
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Congenital anomaly of cardiovascular system 5 trials · 595 incl. sub-types
5 sub-types
- Congenital heart disease 266 trials · 416 incl. sub-types Sub-types →
- Congenital heart malformation 3 trials · 154 incl. sub-types Sub-types →
- Congenital arteriovenous fistula 59 trials · 60 incl. sub-types Sub-types →
- Venous hemangioma 17 trials
- Persistent fetal circulation syndrome 11 trials
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Cardiovascular neoplasm 0 trials · 277 incl. sub-types
5 sub-types
- Vascular neoplasm 3 trials · 271 incl. sub-types Sub-types →
- Cardiovascular cancer 0 trials · 153 incl. sub-types Sub-types →
- Cardiovascular organ benign neoplasm 0 trials · 114 incl. sub-types Sub-types →
- Heart neoplasm 3 trials · 7 incl. sub-types Sub-types →
- Neoplasm of pericardium 0 trials Sub-types →
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Autoimmune disorder of cardiovascular system 0 trials · 3 incl. sub-types
6 sub-types
- Chilblain lupus 1 trial · 3 incl. sub-types Sub-types →
- Libman-Sacks endocarditis 0 trials
- Autoimmune atherosclerosis 0 trials
- Autoimmune cardiomyopathy 0 trials Sub-types →
- Autoimmune vasculitis 0 trials Sub-types →
- Rheumatic pulmonary valve disease 0 trials
Most studied deeper sub-types
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Can a less invasive valve replacement tame a failing aortic valve?
Disease control Stopped earlyThis study is a patient registry that collects information on people with severe aortic stenosis or aortic regurgitation who are treated with the Trilogy heart valve system, a device implanted via a catheter (TAVI) to replace the aortic valve without open-heart surgery. The goal …
Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Heart drug tested to fight COVID-19 complications
Disease control Stopped earlyThis study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…
Phase 2/3 • Sponsor: Cardiol Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Aspirin study for kidney patients halted early – did the risks outweigh the benefits?
Disease control Stopped earlyThis study looked at whether taking a daily low-dose aspirin could help people with chronic kidney disease avoid their first heart attack or stroke. Over 4,600 participants were randomly assigned to take aspirin or receive usual care. The trial was stopped early, and the final re…
Phase 3 • Sponsor: University of Southampton • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Can checking blood pressure at home help kidney transplant patients?
Disease control Stopped earlyThis study tested whether kidney transplant recipients with high blood pressure could better control their condition by monitoring their blood pressure at home, compared to standard clinic visits. The trial planned to enroll many participants but was stopped early after only 21 p…
Sponsor: Oslo University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Can a simple test spot heart damage in cancer survivors?
Diagnosis Stopped earlyThis study looks at whether a special ECG and a blood test can find early signs of heart weakness in adult cancer survivors who had certain chemotherapy. Researchers will check how well these tests work compared to standard heart imaging. The goal is to gather information needed …
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Aug 12, 2026 00:00 UTC
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Aged heart cells may hold clues to heart disease progression after attack
Knowledge-focused Stopped earlyThis study looks at whether heart cells that age rapidly after a heart attack release harmful proteins that make heart disease worse. Researchers will collect blood and heart tissue samples from people undergoing coronary artery bypass surgery after a recent heart attack or for s…
Sponsor: South Tees Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Skin test could warn of hidden blood vessel trouble
Knowledge-focused Stopped earlyThis study looked at how tiny blood vessels in the skin of healthy volunteers respond to substances that make them widen or narrow. Researchers used a mild electrical current to deliver these substances through the skin and measured changes in blood flow with light. The goal was …
Sponsor: University Hospital, Linkoeping • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Painkiller showdown: which is safer for the heart?
Knowledge-focused Stopped earlyThis study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…
Phase 4 • Sponsor: Platelet and Thrombosis Research, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Protein blood test aims to personalize heart care, but study stalls
Knowledge-focused Stopped earlyThis study looked at whether a new blood test called SomaSignal could help doctors make better treatment decisions for people at higher risk of heart disease. The test measures proteins in the blood to predict heart risks. Only 12 people took part before the study was stopped ear…
Sponsor: Intermountain Health Care, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Heart device study in india aims to track AF progression
Knowledge-focused Stopped earlyThis study looked at how Medtronic heart devices detect and manage atrial fibrillation (AF) in Indian patients. It tracked whether the condition became persistent over time. The study enrolled 79 people over 55 with heart devices. It was terminated early, so results are limited.
Sponsor: Medtronic Cardiac Rhythm and Heart Failure • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Heart surgery warning: thin vessel layer may predict deadly complications
Knowledge-focused Stopped earlyThis study aimed to see if measuring the glycocalyx—a thin, protective layer inside blood vessels—before heart surgery could predict serious problems like shock, kidney failure, or death. Researchers planned to include 130 adults having heart surgery with a heart-lung machine. Th…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC