Congenital arteriovenous fistula

This study tests a new device that creates a connection between an artery and a vein using a small needle puncture instead of open surgery. The goal is to provide a reliable access point for dialysis in people with kidney failure. About 126 adults will be enrolled and followed fo…

This study is testing a device called WRAPSODY CIE, a mesh tube placed in veins used for dialysis. The goal is to see if it can keep these veins from narrowing or blocking over time. Researchers will follow 250 people on dialysis for up to 3 years to check how well the device wor…

This trial tests whether leaving the fat around a vein intact during fistula surgery helps the fistula mature for dialysis. Patients with advanced kidney disease needing hemodialysis are randomly assigned to have that fat preserved or removed. The study tracks fistula maturation …

This study is testing a device called the WavelinQ EndoAVF System that creates a connection between an artery and a vein (AV fistula) in people who need dialysis. The goal is to make it easier to start and continue dialysis with fewer complications. About 280 adults with end-stag…

This trial tests whether the direction of the needle bevel (up or down) during fistula puncture affects the risk of complications in people on hemodialysis. About 240 adults with end-stage kidney disease who are starting dialysis with a new arteriovenous fistula will be randomly …

This study is checking how well a device called the Cera Vascular Plug works and if it is safe. The plug is used to block blood flow in certain blood vessels to treat conditions like aneurysms, abnormal connections between arteries and veins, and other problems. About 132 adults …

This study tests whether a short course of the blood thinner apixaban can help new dialysis access points (arteriovenous fistulas) mature properly in people with end-stage kidney disease. About 190 adults will receive either apixaban or a placebo around the time of fistula creati…

This study looks at how well the PHIL Embolic System works to treat a rare brain condition in children called dural arteriovenous fistulas (DAVFs), where blood vessels connect abnormally. About 15 children under 22 will receive the treatment, which uses a special material to bloc…

This study tests a device called LOBO™ to block abnormal blood vessels in the lungs (PAVMs). About 30 people will get the procedure and be followed for 3 years with CT scans to see if the vessels stay closed. The goal is to see how well the device works compared to standard treat…

This study tests a special wrap called SelfWrap that is placed around blood vessels during surgery to create a connection for dialysis. The wrap helps the vessels grow strong and work well without extra procedures. About 600 adults with advanced kidney disease who need a new dial…

This study tests a new liquid embolic agent to treat brain arteriovenous malformations (AVMs), which are tangles of abnormal blood vessels that can cause bleeding or stroke. About 116 adults aged 18 to 80 with certain types of AVMs will receive the treatment and be followed for o…

This study compares two ways to create an arteriovenous fistula (AVF) for dialysis in people with advanced kidney disease. The standard end-to-side method is being tested against a newer piggyback technique that may reduce blockages and failures. About 130 adults who need dialysi…

This study looks at a new way to do dialysis using just one needle in the arm instead of two, which may cause less damage to the blood vessel used for treatment. About 100 adults on long-term dialysis will try this method, and researchers will check if it keeps dialysis working w…

This study is collecting information from up to 10,000 people who receive BALT medical devices for conditions like brain aneurysms, stroke, and blocked arteries. Researchers will track how well the devices work and if any safety issues arise during routine care. The goal is to ga…

This study looks at whether the sounds made by blood flowing through an arteriovenous fistula (AVF) can tell doctors how healthy the fistula is. Researchers will use MRI and ultrasound to measure blood flow and compare it to the sounds recorded. If a clear link is found, it could…