New liquid embolic agent could shrink dangerous brain malformations

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 and ≤ 80 years at the time of signing the informed consent * Subjects with brain arteriovenous malformation diagnosed by CT/MRI/DSA * The target brain arteriovenous malformation is classified by Spetzler-Martin in the range of Ⅰ \~ Ⅳ * Subjects themselves and/or their guardian are able to understand the purpose of the study, consent to participate, and sign the informed consent form * Brain arteriovenous malformations deemed suitable for liquid embolic agent intervention as assessed by the investigator Exclusion Criteria: * Multiple brain arteriovenous malformations * Brain arteriovenous malformation complicated with blood flow-related aneurysm that may require staged and delayed treatment using other methods within the one-year follow-up period * Brain arteriovenous malformation with a history of stereotactic radiosurgery within 3 years * Brain arteriovenous malformation with bleeding within 1 week * Brain arteriovenous malformation with an expected number of embolizations ≥ 4 * Brain arteriovenous malformation scheduled for surgical resection after embolization * mRS score ≥ 3 * Subjects unsuitable for anesthesia or endovascular surgical treatment, due to major diseases of cardio, lung, liver, spleen or kidney, malignant brain tumors, severe active infection, disseminated intravascular coagulation, or a history of severe mental illness, etc * Subjects who undergo major surgical procedures (such as tumor resection, vital organ surgery, etc.) within 30 days prior to signing the informed consent form, or those scheduled for such procedures within 60 days after signing the informed consent form * Contraindications for liquid embolic agent treatment, including but not limited to: contraindications for DSA, severe allergy or intolerance to contrast agents, severe allergy or intolerance to antiplatelet or anticoagulant medications required for treatment, or severe allergy to tantalum metal * Pregnant or lactating women * Subjects participating in other drug or device studies that have not reached their endpoints or who have just withdrawn from the group for less than one month