ARTERIOVENOUS FISTULA

This study tests a special wrap called SelfWrap placed around blood vessels during fistula creation surgery for dialysis. The goal is to help the fistula mature faster and work without needing extra procedures. About 600 adults with chronic kidney disease will take part, and they…

This study is checking how well a device called the Cera Vascular Plug works and if it is safe. It is for people with conditions like aneurysms (bulging blood vessels) or abnormal connections between arteries and veins. The plug is placed into the blood vessel to block blood flow…

This study tests whether a short course of the blood thinner apixaban can help new dialysis fistulas mature properly in people with end-stage kidney disease. About 190 adults will receive either apixaban or a placebo around the time of fistula surgery. The goal is to see if the d…

This study tests a liquid embolic agent that is injected into abnormal blood vessels in the brain to block them. About 116 adults with brain arteriovenous malformation (a tangle of vessels) will receive this treatment or a similar approved device. The goal is to see if the new li…

This study tests a new device that creates dialysis access through a small skin puncture instead of open surgery. It is for adults with kidney failure who need dialysis. The goal is to see if the procedure is safe and works well, with follow-up for up to five years.

This study is testing a device called the BD WavelinQ EndoAVF System, which creates a connection between an artery and a vein in the arm to make dialysis easier. About 280 adults with end-stage kidney disease who need dialysis will take part. The goal is to see if the device work…

This study tests a new way to do dialysis using only one needle in the arm's blood vessel and a second needle in the leg to return cleaned blood. The goal is to reduce damage to the main dialysis blood vessel, lower the risk of complications like scarring and blockages, and cut d…