New hope for Post-Surgery weight regain: drug combo tested

NCT ID NCT05975580

First seen Feb 24, 2026 · Last updated May 16, 2026 · Updated 12 times

Summary

This study tests whether adding weight-loss medications (topiramate, phentermine, or both) to lifestyle counseling can help people who have regained weight after bariatric surgery. About 120 adults who had sleeve gastrectomy or gastric bypass at least 18 months ago and have regained at least 5% of their lowest post-surgery weight will participate. The goal is to see if these drugs can safely and effectively reverse that regain.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • University of California Irvine Medical Center

    RECRUITING

    Orange, California, 92868, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

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