New Tube-Fed diet aims to help obese patients shed pounds

NCT ID NCT05080699

ENROLLING_BY_INVITATION Disease control Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study at Mayo Clinic is testing a special low-calorie, high-protein tube feeding formula called Peptamen Intense VHP in 12 obese patients who rely on tube feeding. The goal is to see if it helps them lose weight while maintaining muscle mass, and also improves blood pressure, blood sugar, and cholesterol. The study is small and early, so results will need confirmation in larger trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Peptamen Intense VHP (a high-protein, low-calorie tube feeding formula)
What this could lead to: If it works, this could offer a safe way for obese patients who rely on tube feeding to lose weight and improve health markers like blood pressure and blood sugar.
What could go wrong: This is a very small pilot study with only 12 participants, so results may not apply to everyone. The formula may cause digestive issues or not lead to significant weight loss.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY

Contacts and locations

Locations

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

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