New monthly weight loss shot shows promise in Mid-Stage trial

NCT ID NCT06973720

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests a new drug called MET097, given as a shot, to help people with obesity or overweight lose weight. After 12 weekly doses, participants switch to monthly shots for up to 64 weeks. The trial compares four different dose schedules against a placebo to see which works best and is safest. About 268 people without type 2 diabetes are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CenExel iResearch, LLC

    Decatur, Georgia, 30030, United States

  • CenExel iResearch, LLC

    Savannah, Georgia, 31405, United States

  • ForCare Clinical Research

    Tampa, Florida, 33613, United States

  • Hassman Research Institute

    Marlton, New Jersey, 08053, United States

  • Research Centers of America

    Hollywood, Florida, 33024, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MET097 (a weight loss drug given as a shot)

What this could lead to

If successful, this could lead to a monthly injection for weight loss, offering a more convenient option than weekly shots.

What could go wrong

This is a mid-stage trial with only 268 people, so results may not hold in larger studies. Side effects are possible, and the drug may not work for everyone.

Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.