Vitamin k shows promise for aching knees in small trial

NCT ID NCT05505552

First seen Nov 01, 2025 · Last updated Jun 05, 2026 · Updated 34 times

Summary

This pilot study tested whether taking a daily vitamin K supplement for 6 months could improve knee function in 37 adults aged 50+ with mild-to-moderate knee osteoarthritis and low vitamin K levels. Participants were randomly assigned to receive either vitamin K or a placebo. The main goal was to gather data for a larger future study, including how well people stick with the treatment and whether vitamin K affects markers of joint health.

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Contacts and locations

Locations

  • Tufts University

    Boston, Massachusetts, 02111, United States

  • UMass Memorial Medical Center

    Worcester, Massachusetts, 01605, United States

  • University of North Carolina Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

Conditions

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