New knee injection shows promise for arthritis sufferers
NCT ID NCT05079035
First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 28 times
Summary
This study tested a single injection of TTAX03 in 90 adults with severe knee osteoarthritis (grades 3-4). The goal was to see if it reduces pain and improves function better than a placebo (saline) injection after 12 weeks. Researchers measured how many people felt at least a 20-50% improvement in pain, daily function, or overall well-being.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alabama Orthopaedic Center
Birmingham, Alabama, 35243, United States
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Gulfcoast Research Institute
Sarasota, Florida, 34232, United States
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Horizon Clinical Research
La Mesa, California, 91942, United States
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Manage Sites/The Ohio State University Wexner Medical Center, Sports Medicine The Ohio State University Wexner Medical Center, Sports Medicine
Columbus, Ohio, 43201, United States
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Ochsner Health Center
Jefferson, Louisiana, 70121, United States
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Paragon Sports Medicine
Atlanta, Georgia, 30327, United States
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Precision Clinical Research
Sunrise, Florida, 33351, United States
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Rothman Orthopaedic Institute
Media, Pennsylvania, 19063, United States
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Tuscon Orthopedic Institute
Tucson, Arizona, 85712, United States
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UAB Orthopaedic Surgery
Birmingham, Alabama, 35205, United States
Conditions
Explore the condition pages connected to this study.