Can a simple drug cut blood loss during knee replacement?
NCT ID NCT07174895
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looked at whether giving tranexamic acid (a drug that helps blood clot) during knee replacement surgery reduces blood loss, and if a surgical drain is still needed. 192 patients with knee osteoarthritis were split into three groups: one got the drug plus a drain, one got the drug only, and one got a drain only. The goal was to see which approach leads to less bleeding and fewer transfusions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tranexamic acid
- What this could lead to
- If successful, this could help surgeons reduce blood loss and transfusion needs during knee replacement, improving recovery.
- What could go wrong
- This is a small, completed study from a single region, so results may not apply broadly. Tranexamic acid can rarely cause blood clots.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OSTEOARTHRITIS, KNEE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculity of Medicine
Idlib, Syria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a common painkiller sabotage your knee treatment?
- Can a Mind-Body program ease knee pain and lift mood?
- Which knee implant feels more natural? a trial puts two designs to the test
- Could a quick insulin shot stop Steroid-Induced blood sugar spikes?
- Which Nerve-Blocking technique offers better knee pain relief?
- Knee replacement pain: can a simple injection match a nerve block?