Targeted cancer drug shows promise but study halted early
NCT ID NCT04985604
First seen Oct 31, 2025 · Last updated May 16, 2026 · Updated 27 times
Summary
This study tested a drug called tovorafenib in people aged 12 and older whose cancers had returned or worsened and had certain gene changes (MAPK pathway). The goal was to see if the drug could shrink tumors. The study was stopped early, so results are limited.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Antwerp University Hospital
Edegem, Belgium
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Asan Medical Center
Seoul, South Korea
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Cancer Specialists of North Florida
Jacksonville, Florida, 32256, United States
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Community North Cancer Center
Indianapolis, Indiana, 46250, United States
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Dong-A University Hospital
Busan, South Korea
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Hoag Health
Newport Beach, California, 92663, United States
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Hopital de La Timone - APHM
Marseille, Bouches-du-Rhône, France
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Hospital Clinic Barcelona
Barcelona, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, Spain
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Hospital Universitario Ramón y Cajal
Madrid, Spain
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Monash Medical Centre
Clayton, Victoria, Australia
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OHSU Knight Cancer Institute
Portland, Oregon, 97239, United States
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Princess Margaret Cancer Centre
Toronto, Ontario, Canada
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Samsung Medical Center
Seoul, South Korea
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Severance Hospital, Yonsei University Health System
Seoul, South Korea
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The Angeles Clinic
Los Angeles, California, 90025, United States
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The Hospital for Sick Children
Toronto, Ontario, Canada
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15213, United States
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University of Colorado Hospital
Aurora, Colorado, 80045, United States
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Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37232, United States
Conditions
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