Could a Weight-Loss drug slow endometrial cancer growth?

NCT ID NCT07065552

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether tirzepatide, a drug used for weight loss and diabetes, can slow tumor growth in people with obesity-driven endometrial cancer. About 20 participants will take the drug before their scheduled hysterectomy. Researchers will compare cancer cell activity in tissue samples taken before and after treatment to see if the drug reduces tumor growth.

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Conditions

The condition(s) this trial relates to.

endometrial cancer endometrium neoplasm Insulin Resistance Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Lineberger Comprehensive Cancer Center

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact