New combo aims to melt fat, save muscle in obesity battle
NCT ID NCT05933499
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining tirzepatide (a weight-loss drug) with bimagrumab (an experimental drug) helps people with obesity lose mostly fat while keeping muscle and bone. 63 adults will receive either the combo, tirzepatide alone, or bimagrumab alone for 52 weeks. The goal is to improve body composition and insulin sensitivity without the usual muscle loss seen with weight loss.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••