Electric fields aimed deep inside the brain without surgery – a new way to study the mind

NCT ID NCT07663578

Recruiting now Knowledge-focused Sponsor: University of California, Davis Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study explores how a technique called Temporally Interfering Electric Fields Stimulation (TIEFS) affects brain activity and thinking. TIEFS uses electrodes on the scalp to send electrical currents that can reach deep brain areas without surgery. Researchers will test it in adults with epilepsy who already have brain monitoring implants, as well as in healthy volunteers. Participants complete thinking tasks and have their brain signals recorded during brief stimulation sessions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Temporal Interference Electrical Stimulation (TIEFS)
What this could lead to: If successful, this could pave the way for a non-surgical brain stimulation treatment for epilepsy and other neurological conditions.
What could go wrong: This is a very small, early-stage study focused on measuring brain signals, not treating disease. The approach may not produce clear or clinically useful results.

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Conditions

The condition(s) this trial relates to.

epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPILEPSY

Contacts and locations

Locations

University of California Davis Medical Center
RECRUITING

Sacramento, California, 95817, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.