New hope for PBC patients: drug targets debilitating itch

NCT ID NCT06733519

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 32 times

Summary

This study tests a new medicine called TH104 for people with primary biliary cholangitis (PBC) who suffer from moderate to severe itching. About 40 adults will receive either TH104 or a placebo to see if the drug is safe and helps reduce itch. The goal is to improve quality of life by easing this distressing symptom.

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