Scientists launch study to unravel mysterious chronic itch

NCT ID NCT05678309

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study aims to collect blood, skin swabs, skin biopsies, and questionnaire data from 175 adults with chronic itch that has no known skin cause (pruritus sine materia). Researchers hope to better describe the condition and uncover clues about what drives it. Participants will provide samples at the start and fill out surveys about their itch and quality of life over time.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this study could provide a clearer picture of what causes chronic itch without a known skin disease, pointing toward better diagnosis or future treatments.
What could go wrong
This is an observational study, not a treatment trial. It will not directly help participants and may not lead to any new therapies.

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Conditions

The condition(s) this trial relates to.

Pruritus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service de dermatologie, CHRU BREST

    RECRUITING

    Brest, 29200, France

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Other studies related to the condition(s) this trial covers.