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UK trial repurposes cancer drug to fight rare tumors

NCT ID NCT05770544

Recruiting now Disease control Sponsor: Cancer Research UK Source: ClinicalTrials.gov ↗

Summary

This trial is testing if a drug called entrectinib, already approved for some lung cancers, can help control other rare cancers that share the same genetic change (called ROS1-positive). It aims to enroll about 30 adults and children with these rare cancers to see if the drug shrinks their tumors or stops them from growing. The goal is to provide a new treatment option for patients with few other choices.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, CB2 OQQ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Alder Hey Hospital

    RECRUITING

    Liverpool, L14 5AB, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Belfast City Hospital

    RECRUITING

    Belfast, BT9 7AB, United Kingdom

    Contact Email: •••••@•••••

    Contact

  • Birmingham Children's Hospital

    NOT_YET_RECRUITING

    Birmingham, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Bristol Haematology and Oncology Centre

    RECRUITING

    Bristol, BS2 8ED, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Bristol Royal Hospital for Children

    RECRUITING

    Bristol, BS2 8BJ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cardiff Children's Hospital

    NOT_YET_RECRUITING

    Cardiff, CF14 4XW, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Churchill Hospital

    RECRUITING

    Oxford, OX3 7LE, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Clatterbridge Cancer Centre

    RECRUITING

    Metropolitan Borough of Wirral, CH63 4JY, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Freeman Hospital

    RECRUITING

    Newcastle, NE7 7DN, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Great North Children's Hospital

    RECRUITING

    Newcastle, NE1 4LP, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Great Ormond Street Hospital

    RECRUITING

    London, WC1N 3JH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Guy's Hospital

    RECRUITING

    London, SE1 9RT, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • John Radcliffe Hospital

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Leicester Royal Infirmary

    RECRUITING

    Leicester, LE1 5WW, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Royal Hospital for Children Glasgow

    RECRUITING

    Glasgow, G51 4TF, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Royal Manchester Children's Hospital

    NOT_YET_RECRUITING

    Manchester, M13 9WL, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sheffield's Children's Hospital

    RECRUITING

    Sheffield, S10 2TH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Southampton General Hospital

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Beatson Hospital

    RECRUITING

    Glasgow, G12 OYN, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Christie Hospital

    RECRUITING

    Manchester, M20 4BX, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Royal Marsden Hospital

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University College London Hospital

    RECRUITING

    London, NW1 2BU, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University Hospital Birmingham

    RECRUITING

    Birmingham, B15 2TT, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Velindre Cancer Centre

    RECRUITING

    Cardiff, CF14 2TL, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Western General Hospital

    RECRUITING

    Edinburgh, EH4 2XU, United Kingdom

    Contact

    Contact

  • Weston Park Hospital

    RECRUITING

    Sheffield, S10 2SJ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

BRAIN NEOPLASMS CANCER GLIOMA HAEMATOLOGICAL MALIGNANCY LYMPHOPROLIFERATIVE DISORDERS MALIGNANCY MALIGNANT NEOPLASM MELANOMA NEOPLASMS BY HISTOLOGIC TYPE NEOPLASMS BY SITE SOLID TUMOUR