Radioactive antibody takes aim at Hard-to-Treat cancers

NCT ID NCT05204147

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 37 times

Summary

This early-stage study tests a new treatment for people with advanced colorectal or other cancers that make a protein called CEA. The treatment, Ac225-DOTA-M5A, is an antibody that seeks out CEA on cancer cells and delivers a radioactive payload to kill them. The main goals are to find the safest dose and understand side effects. About 20 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.