New cancer drug trial tests immune system booster for tough tumors

NCT ID NCT05070247

Summary

This study tested a new drug called TAK-500, designed to activate the immune system to fight cancer. It was given alone or combined with an existing immunotherapy drug (pembrolizumab) to adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to find a safe dose and see if the treatment could shrink tumors in cancers like lung, pancreatic, and kidney cancer.

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Contacts and locations

Locations

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • New York University

    New York, New York, 10016-4744, United States

  • Northwestern

    Chicago, Illinois, 60611, United States

  • START South Texas Accelerated Research Therapeutics

    San Antonio, Texas, 78229, United States

  • Sarah Cannon Cancer Institute

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute

    Denver, Colorado, 80218, United States

  • Sylvester Comprehensive Cancer Center

    Miami, Florida, 33136, United States

  • Univeristy of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of California San Diego

    La Jolla, California, 92093, United States

  • University of Colorado - Anschutz Medical Campus - PPDS

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.