Experimental virus-antibody combo for tough skin cancer shows early promise but study stopped

NCT ID NCT04163952

First seen Jan 30, 2026 · Last updated May 01, 2026 · Updated 12 times

Summary

This early-phase trial tested a combination of two treatments for advanced skin squamous cell carcinoma: a modified virus that helps the immune system attack tumors (talimogene laherparepvec) and an antibody that blocks cancer growth signals (panitumumab). The study enrolled 5 adults whose cancer had spread or come back. The main goals were to check safety and see how well the combo worked. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Duke University Medical Center - Duke Cancer Center

    Durham, North Carolina, 27710, United States

  • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health

    New York, New York, 10016, United States

  • NYU Langone Medical Center (Tisch Hospital)

    New York, New York, 10016, United States

  • New York University Langone Medical Center

    New York, New York, 10016, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

Conditions

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