Rare cancer hope: immune drug shows promise in phase 2 trial

NCT ID NCT02721732

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a drug called pembrolizumab in 157 people with rare cancers that had spread or couldn't be removed. The drug works by helping the body's immune system attack the cancer. The main goal was to see how many patients were alive and their cancer hadn't grown after 27 weeks of treatment.

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Conditions

The condition(s) this trial relates to.

adrenal cortex carcinoma adrenal cortex neoplasm angiosarcoma cancer cancer of unknown primary site kidney medullary carcinoma malignant adrenal gland pheochromocytoma malignant germ cell tumor metastatic malignant neoplasm metastatic squamous cell carcinoma Neoplasm Metastasis Neoplasms, Unknown Primary paraganglioma penile cancer penile carcinoma penile neoplasm pheochromocytoma pheochromocytoma-paraganglioma renal cell carcinoma skin squamous cell carcinoma small cell carcinoma vascular neoplasm Vascular Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States