STAGE IV RENAL CELL CANCER AJCC V7
Clinical trials for STAGE IV RENAL CELL CANCER AJCC V7 explained in plain language.
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Can a pill keep kidney cancer away after surgery?
Disease control OngoingThis study tests whether the drug pazopanib can delay or prevent kidney cancer from returning in patients who have had all visible tumors removed by surgery. About 129 adults with advanced kidney cancer that spread to other parts of the body but showed no signs of disease after s…
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V7
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 02:14 UTC
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Experimental combo targets cancer cell recycling in Late-Stage tumors
Disease control OngoingThis early-phase trial tests the safety and best dose of two drugs—MK-2206 and hydroxychloroquine—given together to people with advanced solid tumors, melanoma, prostate, or kidney cancer. The goal is to see if blocking a process called autophagy can help kill more cancer cells. …
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V7
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 02:03 UTC
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New drug cocktail shows promise against tough kidney cancer
Disease control OngoingThis study tests a combination of two drugs—entinostat and aldesleukin—for people with kidney cancer that has spread. The goal is to find the safest dose and see if the combo can shrink tumors. About 47 adults with clear cell kidney cancer are taking part.
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V7
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Inhaled therapy shows promise for lung metastases
Disease control OngoingThis study tests an inhaled form of a protein called interleukin-2 (IL-2) to treat cancers that have spread to the lungs, such as melanoma, kidney cancer, and sarcoma. The goal is to find the safest dose and see if it can shrink tumors. About 70 adults with advanced cancer and lu…
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V7
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New immunotherapy cocktail shows promise for advanced kidney cancer
Disease control OngoingThis early-phase study tests whether giving immunotherapy drugs (nivolumab alone or with bevacizumab or ipilimumab) before surgery is safe for people with kidney cancer that has spread. About 104 participants will receive these treatments to see how the body reacts and whether th…
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V7
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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New hope for rare cancers: immune-boosting drug shows promise
Disease control OngoingThis study tests a drug called pembrolizumab in 157 people with rare tumors that cannot be removed by surgery or have spread. The drug helps the immune system fight cancer by blocking a protein that slows it down. The main goal is to see if the drug can stop tumors from growing f…
Matched conditions: STAGE IV RENAL CELL CANCER AJCC V7
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Apr 24, 2026 16:07 UTC