Breathing in a cancer fighter: inhaled IL-2 trial targets lung tumors
NCT ID NCT01590069
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests an inhaled form of interleukin-2 (IL-2), a protein that boosts the immune system, in people whose cancer has spread to the lungs. The goal is to find the best dose and see if it can shrink lung tumors. About 70 adults with cancers like melanoma, sarcoma, or kidney cancer are taking part. The treatment is breathed in through a nebulizer, and researchers monitor side effects and tumor response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- aerosolized interleukin-2 (aldesleukin)
- What this could lead to
- If it works, this could offer a new way to treat lung metastases by boosting the immune system directly in the lungs, potentially controlling tumor growth.
- What could go wrong
- This is an early phase trial with a small number of participants, so the benefits are uncertain. Side effects from immune stimulation may occur, and it may not shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
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