Could stem cells save failing kidneys? mayo clinic launches new trial

NCT ID NCT06752577

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether stem cells from donated bone marrow are safe for people with chronic kidney disease, including those who have had a kidney transplant. Up to 75 participants will receive the cells through an IV or directly into the kidney arteries, with repeat doses allowed every 6 months. The main goal is to check for side effects, not yet to prove the treatment works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bone marrow-derived mesenchymal stem cells (MSCs)
What this could lead to
If successful, this could point toward a new way to slow or manage chronic kidney disease, potentially reducing the need for dialysis or repeat transplants.
What could go wrong
This is an early safety trial with only 75 participants, so it is too soon to know if the stem cells actually help. There are also risks from the infusion procedure, including possible allergic reactions or kidney damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    RECRUITING

    Jacksonville, Florida, 32224, United States

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Other studies related to the condition(s) this trial covers.