Could a donor stem cell transplant fix broken immune systems?
NCT ID NCT03663933
First seen Mar 29, 2026 · Last updated Jun 14, 2026 · Updated 11 times
Summary
This study tests whether a stem cell transplant from a healthy donor can safely treat people with severe T-cell problems. Participants receive chemotherapy and antibody therapy before the transplant to prepare their body, then donor stem cells are given to build a new, healthy immune system. The main goal is to see if patients are alive with mostly donor T-cells and no graft failure 6 months after transplant.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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National Marrow Donor Program
Minneapolis, Minnesota, 55401, United States
Conditions
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