Can a common diabetes drug help transplant patients?

NCT ID NCT00466518

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how sitagliptin (Januvia) affects levels of anti-rejection drugs and blood sugar in 16 people who had a kidney transplant and have type 2 diabetes. Participants took sitagliptin daily for 3 months. The goal was to see if it is safe and works well in this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sitagliptin (Januvia)

What this could lead to

If successful, this could show that sitagliptin is a safe and effective option to help control blood sugar in kidney transplant patients with type 2 diabetes.

What could go wrong

This is a very small, early-phase study with only 16 participants, so results may not apply to everyone. The main goal was to check drug interactions, not to prove long-term benefits or safety.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198-1230, United States