Bionic leg feedback: can a neuroprosthesis bring back sensation for amputees?

NCT ID NCT04658693

Recruiting now Disease control Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 3 times

Summary

This study tests a sensory neuroprosthesis—implanted electrodes that send small electrical currents to remaining nerves—to restore sensation of a missing lower limb in people with diabetic peripheral neuropathy and amputation. The 15 participants will also have the option of muscle recording electrodes to help control a robotic prosthetic leg. Researchers will measure how well the device works and its effect on walking stability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sensory neuroprosthesis (implanted stimulating and recording electrodes)
What this could lead to: If it works, this could help people with limb loss regain sensation and improve walking stability.
What could go wrong: This is a very small early study with only 15 participants, so results may not apply widely. Implant surgery carries risks like infection or nerve damage.

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Conditions

The condition(s) this trial relates to.

diabetic neuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC PERIPHERAL NEUROPATHY LOWER EXTREMITY AMPUTEE

Contacts and locations

Locations

Louis Stokes VA Medical Center, Cleveland, OH
RECRUITING

Cleveland, Ohio, 44106-1702, United States

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