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A ZAP BEHIND THE KNEE MAY QUIET DIABETIC NERVE PAIN

NCT ID NCT07725419

Completed Symptom relief Sponsor: Algiamed Technologies USA, Inc. Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether a non-invasive device that delivers pulsed radiofrequency energy behind the knee can reduce pain and improve function in people with diabetic neuropathy whose pain persists despite medication. About 92 participants will receive either the active device or a sham version once a week for three weeks. Researchers will track pain scores and symptoms over six months to see if the treatment offers meaningful relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a non-invasive pulsed radiofrequency device applied behind the knee
What this could lead to
If it works, this could offer a drug-free option for people with diabetic nerve pain who get little relief from current medications.
What could go wrong
This is a small, early-stage trial with only 92 participants. The placebo effect is strong in pain studies, and the device may not prove better than sham treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot diabetic neuropathy neuralgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC PERIPHERAL NEUROPATHIC PAIN DIABETIC PERIPHERAL NEUROPATHIC PAIN (DPN) DIABETIC PERIPHERAL NEUROPATHY

Contacts and locations

Locations

  • CDE / Clinical Sites - Pretoria

    Pretoria, Gauteng, South Africa

  • Centre for Diabetes and Endocrinology (CDE), Houghton

    Johannesburg, Gauteng, South Africa

  • Clinical Sites - Krugersdorp

    Krugersdorp, Gauteng, South Africa

  • Clinical Sites - West Johannesburg

    Johannesburg, Gauteng, South Africa

  • Diabetic Clinic at the Charlotte Maxeke Hospital

    Johannesburg, Gauteng, South Africa

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