Could ozempic help people with HIV shed pounds?

NCT ID NCT04174755

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether semaglutide (Ozempic) helps people with HIV and obesity lose more weight than diet and exercise alone. About 80 participants will receive either semaglutide injections or standard lifestyle advice for 28 weeks. Researchers will also check how the drug affects immune function and metabolism.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Semaglutide (Ozempic)
What this could lead to
If it works, this could offer a new weight-loss option for people with HIV who struggle with obesity.
What could go wrong
This is a small, early-stage study with only 80 participants, so results may not apply to everyone. Semaglutide can cause side effects like nausea and vomiting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mater Misericordiae University Hospital

    RECRUITING

    Dublin, Dublin, D07 R2WY, Ireland

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