Could ozempic help people with HIV shed pounds?

NCT ID NCT04174755

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether semaglutide (Ozempic) helps people with HIV and obesity lose more weight than diet and exercise alone. About 80 participants will receive either semaglutide injections or standard lifestyle advice for 28 weeks. Researchers will also check how the drug affects immune function and metabolism.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Semaglutide (Ozempic)

What this could lead to

If it works, this could offer a new weight-loss option for people with HIV who struggle with obesity.

What could go wrong

This is a small, early-stage study with only 80 participants, so results may not apply to everyone. Semaglutide can cause side effects like nausea and vomiting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease Obesity obesity disorder Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mater Misericordiae University Hospital

    RECRUITING

    Dublin, Dublin, D07 R2WY, Ireland

    Contact Email: •••••@•••••