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Weekly shot helps asians with obesity shed pounds in major trial

NCT ID NCT04998136

Completed Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a weekly injection of semaglutide (2.4 mg) helps Asian adults with obesity (BMI 25 or higher) lose weight. About 150 participants received either the drug or a placebo for 44 weeks, along with diet and exercise advice. The main goal was to see how much weight they lost. The drug is meant to be taken long-term to keep weight off, so it controls the condition rather than curing it.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY

Contacts and locations

Locations

  • Ajou University Hospital

    Suwon, 16499, South Korea

  • Dongguk University Ilsan Hospital_Gyeonggi-do

    Gyeonggi-do, 10326, South Korea

  • Gachon University Gil Hospital

    Incheon, 405-760, South Korea

  • Hallym University Sacred Heart Hospital

    Gyeonggi-do, 14068, South Korea

  • King Chulalongkorn Memorial Hospital_Bangkok

    Bangkok, 10330, Thailand

  • King Chulalongkorn Memorial Hospital_Endocrinology

    Bangkok, 10330, Thailand

  • King Chulalongkorn Memorial Hospital_Obstetrics&Gynecology

    Bangkok, 10330, Thailand

  • Konyang University Hospital

    Daejeon, 35365, South Korea

  • Maharaj Nakorn Chiang Mai_Hematology and Oncology

    Chiang Mai, 50200, Thailand

  • Obstetrics&Gynecology King Chulalongkorn Memorial Hospital

    Bangkok, 10330, Thailand

  • Ramathibodi Hospital_Nutrition and Biochemical

    Bangkok, 10400, Thailand

  • SMG-SNU Boramae Medical Center

    Seoul, 07061, South Korea

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Siriraj Hospital_Bangkok_1

    Bangkok, 10700, Thailand

  • Siriraj Hospital_Dept Cardio

    Bangkok, 10700, Thailand

  • Siriraj Institute of Clinical Research

    Bangkok, 10700, Thailand

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