Glowing dye could help surgeons remove sarcomas in one go

NCT ID NCT06409013

Recruiting now Diagnosis Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 05, 2026 · Updated 3 times

Summary

This study tests whether a dye called indocyanine green can help surgeons see if any cancer remains after removing a sarcoma. About 50 adults with bone or soft tissue sarcoma will receive the dye during surgery, and the surgeon will check for glowing areas that might indicate leftover tumor. The goal is to see if this technique matches lab results and could reduce the need for follow-up surgeries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: indocyanine green dye
What this could lead to: If it works, this could help surgeons remove sarcomas more completely in one operation, reducing the need for additional surgeries.
What could go wrong: This is a small, early study with only 50 participants. The dye may not always match lab results, and some people may have allergic reactions.

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Conditions

The condition(s) this trial relates to.

bone cancer bone sarcoma sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BONE SARCOMA SOFT TISSUE SARCOMA

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Mayo Clinic in Rochester
RECRUITING

Rochester, Minnesota, 55905, United States

Contact Email: •••••@•••••

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