Engineered immune cells aim to calm liver damage in first human trial
NCT ID NCT06823713
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 27 times
Summary
This study tests a new treatment called RTX001 for people with severe liver cirrhosis that has caused complications. RTX001 uses a patient's own immune cells (macrophages) that are modified in a lab to reduce inflammation and scarring in the liver. The trial will enroll 30 adults and focus on safety, side effects, and whether the therapy can slow disease progression.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Bristol Royal Infirmary
RECRUITINGBristol, BS2 8HW, United Kingdom
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Glasgow Royal Infirmary
RECRUITINGGlasgow, G4 0SF, United Kingdom
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Hospital General Universitario Gregorio Marañon
RECRUITINGMadrid, 28007, Spain
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Hospital Universitari Vall d'Hebron
RECRUITINGBarcelona, 08035, Spain
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Hospital Universitario La Paz
RECRUITINGMadrid, 28046, Spain
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Hospital Universitario Ramón y Cajal
RECRUITINGMadrid, 28034, Spain
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Hospital Universitario Reina Sofía
RECRUITINGCórdoba, 14004, Spain
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Hospital Universitario Virgen del Rocío
RECRUITINGSeville, 41013, Spain
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King's College Hospital
RECRUITINGLondon, SE5 9RS, United Kingdom
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Nottingham University Hospital
RECRUITINGNottingham, NG5 1PB, United Kingdom
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Royal Infirmary of Edinburgh
RECRUITINGEdinburgh, EH16 4SA, United Kingdom
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Royal Liverpool University Hospital
RECRUITINGLiverpool, L7 8YE, United Kingdom
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St George's Hospital
RECRUITINGLondon, SW17 0QT, United Kingdom
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St Mary's Hospital
RECRUITINGLondon, W2 1NY, United Kingdom
Conditions
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