END-STAGE LIVER DISEASE (ESLD)
Clinical trials for END-STAGE LIVER DISEASE (ESLD) explained in plain language.
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Less fluid, fewer complications? trial tests new strategy in liver transplants
Disease control Recruiting nowThis trial compares two ways of managing fluids during liver transplant surgery in adults with end-stage liver disease. One strategy limits fluids and uses medications to maintain blood pressure, while the other gives more fluids to optimize heart function. The goal is to see whi…
Matched conditions: END-STAGE LIVER DISEASE (ESLD)
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Engineered immune cells aim to calm liver scarring in first human trial
Disease control Recruiting nowThis study tests a new treatment called RTX001 for people with severe liver scarring (cirrhosis) that has led to complications. RTX001 uses the patient's own immune cells, modified in a lab to reduce inflammation and scarring. The trial will enroll 30 adults to check if the thera…
Matched conditions: END-STAGE LIVER DISEASE (ESLD)
Phase: PHASE1, PHASE2 • Sponsor: Resolution Therapeutics Limited • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Can a simple drug make liver transplants safer?
Disease control Recruiting nowThis study tests whether a medicine called tranexamic acid can reduce blood loss during adult liver transplant surgery. About 1,546 people will be randomly assigned to receive either the drug or a placebo. The main goal is to see if the drug works better than placebo at controlli…
Matched conditions: END-STAGE LIVER DISEASE (ESLD)
Phase: NA • Sponsor: RenJi Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Massive european study aims to redefine success in liver transplants
Knowledge-focused Recruiting nowThis study is collecting information from 10,000 liver transplant patients across Europe to create a new, up-to-date reference for what good outcomes look like when using machine perfusion (a technique that keeps donated livers healthier before transplant). The goal is to help do…
Matched conditions: END-STAGE LIVER DISEASE (ESLD)
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC