Robot vs surgeon: which knee replacement works better?

NCT ID NCT07201207

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares robotic-assisted knee replacement to the traditional manual method in 170 adults aged 50-80 with end-stage knee arthritis. Participants are randomly assigned to one of the two surgeries and followed for 2 years to measure knee function, recovery speed, and cost, with a 10-year check for complications. The goal is to see if robotic guidance leads to better outcomes and fewer problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Robotic-assisted total knee arthroplasty (MAKO) vs manual total knee arthroplasty

What this could lead to

If robotic-assisted knee replacement proves better, it could lead to improved function, faster recovery, and fewer complications for people with severe knee arthritis.

What could go wrong

This is a single-center trial with 170 participants, so results may not apply to everyone. The difference between methods might be small, and robotic surgery is more expensive.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••