Robot vs surgeon: which knee replacement works better?

NCT ID NCT07201207

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares robotic-assisted knee replacement to the traditional manual method in 170 adults aged 50-80 with end-stage knee arthritis. Participants are randomly assigned to one of the two surgeries and followed for 2 years to measure knee function, recovery speed, and cost, with a 10-year check for complications. The goal is to see if robotic guidance leads to better outcomes and fewer problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Robotic-assisted total knee arthroplasty (MAKO) vs manual total knee arthroplasty
What this could lead to
If robotic-assisted knee replacement proves better, it could lead to improved function, faster recovery, and fewer complications for people with severe knee arthritis.
What could go wrong
This is a single-center trial with 170 participants, so results may not apply to everyone. The difference between methods might be small, and robotic surgery is more expensive.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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